Las Vegas Raiders vs LA Chargers Prediction 9/15/25 NFL Picks Today

The Los Angeles Chargers and the Las Vegas Raiders meet in week 2 NFL action from Allegiant Stadium on Monday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Los Angeles Chargers vs. Las Vegas Raiders prediction.

Los Angeles Chargers Recap

The Los Angeles Chargers come into this game looking to add on to their 27-21 win over the Kansas City Chiefs last time out to start the year at 1-0. After this game, the Chargers will head home for their home opener against the Denver Broncos.

Chargers Looking To Continue Strong Start To Season

Justin Herbert threw for 318 yards and 3 touchdowns on 25 of 34 passing while also rushing for 32 yards on 7 carries. Omarion Hampton added a team-high 48 rushing yards on 15 carries while Quentin Johnston chipped in a team-high 5 catches for 79 yards and 2 touchdowns. Ladd McConkey added 6 grabs for 74 yards while Keenan Allen had a team-high 7 receptions for 68 yards and a touchdown. Tyler Conklin also added a pair of receptions for 50 yards as well. On defense, Alohi Gilman added 9 total tackles including 4 solo tackles while Daiyan Henley and Da’Shawn Hand each had a sack in the win for Los Angeles.

Why the Los Angeles Chargers will win

Los Angeles Chargers Player Prop Facts

Las Vegas Raiders Recap

The Las Vegas Raiders come into this game looking to build on their 20-13 win over the New England Patriots last time out to start the year at 1-0. After this game, the Raiders will head on the road for a game against the Washington Commanders. 

Raiders Looking For Another Upset To Start Year

Geno Smith threw for 362 yards, a touchdown and an interception on 24 of 34 passing while Ashton Jeanty led the Raiders on the ground with 38 rushing yards and a score on his 19 carries. Brock Bowers led Las Vegas’ receiving group with 5 catches for 103 yards while Jakobi Meyers had a team-high 8 receptions for 97 yards and Tre Tucker had a pair of catches for 54 yards and a touchdown. On defense, Devin White had a team-high 11 total tackles including 8 solo tackles while Tyree Wilson, Malcolm Koonce, Maxx Crosby and Jonah Laulu all had a sack in the win. Isaiah Pola-Mao also chipped in an interception for the Raiders’ defense in the victory.

Why the Las Vegas Raiders will win

Las Vegas Raiders Player Prop Facts

Total Points Facts

Los Angeles Chargers vs. Las Vegas Raiders Prediction

I’m on the Chargers here. It’s not a game I’m rushing to the window to bet, but between two teams that had a nice showing in their openers, I just feel like positive results are going to be easier for the Chargers to sustain given the pieces and makeup of their roster. The Raiders are a solid group and solid home team that I think will surprise some people and provide value at times this season, but with this only being week 2, I think we have to go with what we know and that to me ends up with backing the Chargers here. Give me Los Angeles laying the points here.

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