Eagles vs Rams Prediction 9/21/25 NFL Picks Today

The Los Angeles Rams and the Philadelphia Eagles meet in week 3 NFL action from Lincoln Financial Field on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Eagles vs Rams Prediction.

Los Angeles Rams Recap

The Los Angeles Rams come into this game looking to build on their 2-0 start to the year after picking up a 33-19 win over Tennessee last time out. After this game, the Rams will head home for a game against the Indianapolis Colts.


Rams Looking To Spring Road Upset

Matthew Stafford has thrown for 543 yards, 3 touchdowns and an interception on 71% passing while Kyren Williams has rushed for 132 yards and a touchdown to lead the Rams on the ground. Puka Nacua has a team-high 18 catches for 221 yards while Davante Adams has 10 grabs for 157 yards and a touchdown. On defense, Nate Landman has a team-high 18 total tackles while Kam Curl has 17 total tackles including a team-high 13 solo tackles. Byron Young has a team-high 3 sacks while the Rams’ defense as a whole has combined for 8 sacks and an interception so far this season.

Why the Los Angeles Rams will win

Los Angeles Rams Player Prop Facts

Philadelphia Eagles Recap

The Philadelphia Eagles come into this game looking to add on to their 20-17 win over the Chiefs last time out to sit at 2-0 on the year. After this game, the Eagles will head on the road for a game against the Tampa Bay Buccaneers.

Eagles Win Super Bowl Rematch

Jalen Hurts has thrown for 253 yards on 75.6% passing while also rushing for 3 touchdowns. Saquon Barkley leads the Eagles with 148 rushing yards and 2 touchdowns while DeVonta Smith has a team-high 7 grabs for 69 yards and Dallas Goedert has 7 receptions as well this season. On defense, Zack Baun has a team-high 15 total tackles including 11 solo tackles while the Eagles’ defense as a whole has combined for 2 sacks and an interception this season.

Why the Philadelphia Eagles will win

Philadelphia Eagles Player Prop Facts

Total Points Facts

Eagles vs Rams Prediction

I’m on the Under in this one. I think that the Rams will face a stiffer test here against this Eagle defense and could be closer to the low-scoring output we saw in week one against Houston. But I also think this Rams defense is legit, and we’re seeing the Eagles go with a more run heavy, clock dominant approach. I’m rocking with the under in this one.

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