Raiders vs Colts Prediction 10/5/25 NFL Picks Today

In this article, we will formulate a Raiders vs Colts Prediction for this NFL Week 5 game on Sunday, October 5th at the Lucas Oil Stadium. Let’s take a look at the prediction for this NFL matchup.

Indianapolis Colts Preview

The Indianapolis Colts have a 3-1 record this season and are sitting on the first place of the AFC South. They are 3-1-0 ATS, 2-2-0 in Over/Under and have a 1-1 away record and 2-0 home record. The Colts are coming off a 20-27 road loss to the Los Angeles Rams and are playing the Arizona Cardinals and the Los Angeles Chargers next.

Offensively, the Colts average 30.8 points per game, which ranks 4th in the NFL. Defensively, they allow 20.8 points per game, which is 12th. Indianapolis averages 397.3 total yards per game, with 136.3 rushing yards and 261 passing yards per game. They allow 319.8 total yards per game, with 96.0 rushing and 223.8 passing yards per game.

Daniel Jones leads the Colts with 1078 passing yards and 71.9% completed passes. Jonathan Taylor leads the team in rushing yards, with 414, while Michael Pittman Jr. has a team-high 21 caught passes for 234 receiving yards, and has 3 touchdowns. Defensively, Nick Cross has a team-high 34 total tackles, 20 of them solo. Tyquan Lewis leads the Colts in sacks, with two, while Camryn Bynum has two interceptions.

Las Vegas Raiders Preview

The Las Vegas Raiders have a 1-3 record this season and are sitting on the fourth place of the AFC West. They are 1-3-0 ATS, 2-2-0 in Over/Under and have a 1-1 away record and 0-2 home record. The Raiders are coming off a 24-25 home loss by the Chicago Bears and are playing the Tennessee Titans and the Kansas City Chiefs next.

Offensively, the Raiders average 19.3 points per game, which ranks 24th in the NFL. Defensively, they allow 24.8 points per game, which is 22nd. Las Vegas averages 329.5 total yards per game, with 114.3 rushing yards and 215.3 passing yards per game. They allow 331 total yards per game, with 102.8 rushing and 228.3 passing yards per game.

Geno Smith leads the Raiders with 948 passing yards and 63.8% completed passes. Ashton Jeanty leads the team in rushing yards, with 282, while Jakobi Meyers has a team-high 21 caught passes for 258 receiving yards. Defensively, Devin White has a team-high 34 total tackles, 25 of them solo. Jonah Laulu leads the Raiders in sacks, with 3, while Maxx Crosby has one interception.

Las Vegas Raiders @ Indianapolis Colts Betting Trends: Week 5

 

Why the Indianapolis Colts will win

Why the Las Vegas Raiders will win

Total Points Facts

Indianapolis Colts Player Prop Facts

Las Vegas Raiders Player Prop Facts

Matchup/League Facts

Raiders vs Colts Prediction

In their previous meeting in 2023, the Colts won 23-20 at home, and are 7-3 in their last 10 meetings against the Raiders. Both teams are tied 2-2 wins in their last 4 meetings in Indianapolis, and over is 6-1 in their last 7 meetings.

In this Raiders vs Colts Prediction, the Colts are coming as -7-point home favorites, with the total set at 48 points. The Colts have lost only once in their four games played this season, and have won and covered both of their home games. On the flip side, the Raiders have lost three straight, and did not cover in any of them. The Colts are better both offensively and defensively, winning by an average of 10 points this season, and I like them to get the job done at home in this one. Take the Indianapolis Colts and lay the -7 points.

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