San Francisco 49ers vs Denver Broncos Prediction 10/4/26 NFL Picks Today

The Denver Broncos and the San Francisco 49ers meet in week 4 NFL action from Levi’s Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Denver Broncos vs. San Francisco 49ers prediction.

Denver Broncos Recap

The Denver Broncos come into this game looking to add on to their 30-26 win over the Los Angeles Rams last time out to improve to 2-1 on the year. After this game, the Broncos will head on the road for a matchup against the Los Angeles Chargers.

Broncos Win Back-To-Back Games

Bo Nix has thrown for 605 yards, 4 touchdowns and 3 interceptions on 60.2% passing while J.K. Dobbins leads Denver in rushing with 121 yards and 0 touchdowns through 3 games this season. Jonah Coleman sits behind Dobbins on the ground with 39 yards and 1 TD. Jaylen Waddle leads the Broncos in receiving with 150 yards and 11 catches along with 0 TDs, while Pat Bryant trails with 86 yards and 6 catches. On defense, Alex Singleton has a team-high 33 tackles while Denver’s defense as a whole has combined for 8 sacks and 4 interceptions through 3 games this season.

San Francisco 49ers Recap

The San Francisco 49ers come into this game looking to build on their 36-30 win over Arizona last time out to sit at 3-0 on the year. After this game, San Francisco will head on the road for a game against the Seattle Seahawks.

49ers Looking To Stay Undefeated

Brock Purdy has thrown for 789 yards, 9 touchdowns and 1 interception on 72.3% passing while Christian McCaffrey leads San Francisco in rushing with 166 yards and 3 touchdowns through 3 games this season. Kaelon Black sits behind McCaffrey on the ground with 107 yards and 0 TDs. George Kittle leads the 49ers in receiving with 174 yards and 12 catches along with 3 TDs, while Deebo Samuel Sr. trails with 159 yards and 9 catches. On defense, Fred Warner has a team-high 33 tackles while San Francisco’s defense as a whole has combined for 6 sacks and 1 interception through 3 games this season.

Denver Broncos @ San Francisco 49ers Betting Trends: Week 4

 

Why the San Francisco 49ers will win

Why the Denver Broncos will win

Total Points Facts

San Francisco 49ers Player Prop Facts

Denver Broncos Player Prop Facts

Matchup/League Facts

Denver Broncos vs. San Francisco 49ers Prediction

I’m on the Broncos and the points in this one. I get the allure of backing the 49ers, but they’re banged up like nobody’s business, and this is a Broncos team that lokoed really solid offensively once they woke up in the second half against the Rams. I think the Broncos come out with a bigger sense of urgency here, and I think the Broncos at least cover if not win outright. Give me the Broncos.

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