Titans vs Texans Prediction 9/28/25 NFL Picks Today

In this article, we will formulate a Titans vs Texans Prediction for this NFL Week 4 game on Sunday, September 28th at the NRG Stadium. Let’s take a look at the prediction for this NFL matchup.

Houston Texans Preview

The Houston Texans have a 0-3 record this season and are sitting in 3rd place of the AFC South. They are 0-3 ATS, 0-3 in Over/Under and have a 0-1 home record and 0-2 away record. The Texans are coming off a 10-17 road loss to Jacksonville Jaguars and are playing Baltimore Ravens and Seattle Seahawks next.

Offensively, the Texans average 12.7 points per game, which ranks 32nd in the NFL. Defensively, they allow 17.0 points per game, which is 5th. Houston averages 267.3 total yards per game, with 95.0 rushing yards and 172.3 passing yards per game. They allow 315.7 total yards per game, with 95.0 rushing and 172.3 passing yards per game.

C.J. Stroud leads the Texans with 599 passing yards and 64.0% completed passes. Nick Chubb leads the team in rushing yards, with 141, while Nico Collins has a team-high 14 caught passes for 181 receiving yards, and has two touchdowns. Defensively, Azeez Al-Shaair has a team-high 25 total tackles, 15 of them solo. Will Anderson leads the Texans in sacks, with three, while Jalen Pitre has one interception.

Tennessee Titans Preview

The Tennessee Titans have a 0-3 record this season and are sitting on the 3rd place of the AFC South. They are 1-2 ATS, 2-1 in Over/Under and have a 0-2 home record and 0-1 away record. The Titans are coming off a 20-41 home loss to the Indianapolis Colts and are playing the Arizona Cardinals and Las Vegas Raiders next.

Offensively, the Titans average 17.0 points per game, which ranks 28th in the NFL. Defensively, they allow 31.3 points per game, which is 30th. Tennessee averages 204.3 total yards per game, with 57.3 rushing yards and 147.0 passing yards per game. They allow 373.7 total yards per game, with 145.7 rushing and 228.0 passing yards per game.

Cam Ward leads the Titans with 506 passing yards and 54.5% completed passes. Tony Pollard leads the team in rushing yards, with 197, while Elic Ayomanor has a team-high 8 caught passes for 111 receiving yards, and has two touchdowns. Defensively, Cody Barton has a team-high 20 total tackles, 12 of them solo. Dre’Mont Jones leads the Titans in sacks, with one, while Xavier Woods has one interception.

Tennessee Titans @ Houston Texans Betting Trends: Week 4

 

Why the Houston Texans will win

Why the Tennessee Titans will win

Total Points Facts

Houston Texans Player Prop Facts

Tennessee Titans Player Prop Facts

Matchup/League Facts

Titans vs Texans Prediction

Both teams were tied 1-1 wins last season, with each one winning on the road. Texans won in Tennessee by 23-14 and the Titans in Houston by 32-27. The Texans are 4-1 in their last 5 meetings against the Titans, and 7-2 ATS in their last 9 meetings. The Titans are 4-1 in their last 5 visits in Houston.

In this Titans vs Texans Prediction, the Texans are coming as -7-point home favorites, with the total set at 38.5 points. Both offenses have been terrible this season, as both teams score 29.7 points per game, with the Texans having the worst offense in the NFL. Houston also boasts the 5th-best defense, allowing just 17 points per game, so I expect a low-scoring grind between two struggling teams looking for their first win of the season. Take the under 38.5 points in this one.

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