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Virginia vs. Louisville - 9/22/18 College Football Pick, Odds, and Prediction

Louisville Cardinals (2-1) at Virginia Cavaliers (2-1)
Date & Time Saturday September 22, 2018, 12:30 PM (EDT)
The Line
The Line: Virginia Cavaliers -3 -- Over/Under:
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CFB | Louisville Cardinals (2-1) at Virginia Cavaliers (2-1)
Jamie Rhodes-USA TODAY Sports

The Louisville Cardinals will visit the Virginia Cavaliers in college football activity on Saturday from Scott Stadium. 

Louisville enters this matchup with a 2-1 record overall. The Cardinals were stomped by Alabama 51-14 in the opener, but then caught a groove with wins over Indiana State 31-7 and Western Kentucky 20-17. 

In that WKU game, Louisville QB Malik Cunningham posted 88 yards through the air and also led the team in rushing with 21 carries for 129 yards. Jaylen Smith was the top Cards receiver with 38 yards. 

Over on the Virginia side, they’re currently 2-1 as well, with a loss to Indiana 20-16 sandwiched in between wins over Richmond 42-13 and Ohio 45-31. 

In the Ohio game, Virginia QB Bryce Perkins had a nice outing with 379 yards and three scores, while Jordan Ellis posted three more scores and 171 yards on the ground. Olamide Zaccheaus went off for 247 yards and two TDs to lead the Cavs in receiving. 

The Cardinals are 7-18-1 ATS in their last 26 overall and 3-9 ATS in their last 12 following an ATS loss. Louisville is 2-9 ATS versus a team with a winning record and 0-6 ATS in their last six in September. 

Meanwhile, the Cavaliers are 5-0 ATS in their last five in September and 7-2 ATS versus a team with a winning record. Virginia is 5-2 ATS in their last seven home games and 11-5-1 ATS in their last 17 following an ATS win. 

Louisville had the great misfortune of running into the Alabama buzzsaw their first game out, but then looked like they recovered in game two. The WKU result is a little off-putting however, as the Cardinals became completely one-dimensional and barely got out with a win. I’m not confident that strategy will work too well against Virginia, so I’m going with the Cavaliers for the cover here.

Virginia Cavaliers -3

Andrew has been with Sports Chat Place since 2012, contributing to football, baseball and basketball across the fantasy, college and professional ranks. His goal is to break down the complicated trends and numbers into a language that's accessible even if you're not a seasoned sports bettor, providing comprehensive insight that can apply to just about everyone. Follow Andrew on Twitter for links to his latest Sports Chat Place picks. 

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