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Indianapolis Colts vs. San Diego Chargers - 9/25/16 NFL Pick, Odds, and Prediction

San Diego Chargers (1-1) at Indianapolis Colts (0-2)
Date & Time Sunday September 25, 2016, 4:25 PM (EDT)
The Line
The Line: Indianapolis Colts -3 -- Over/Under: 50.5
TV Channel
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NFL | San Diego Chargers (1-1) at Indianapolis Colts (0-2)

On Sunday, September 25 in Week 3 NFL action from Lucas Oil Stadium, the San Diego Chargers will be visiting the Indianapolis Colts. 

San Diego comes into this game at 1-1 following a 38-14 blowout of the Jaguars in Week 2. The Chargers were in immediate control of this game, getting the score up to 35-0 entering the fourth. San Diego QB Philip Rivers was an efficient 17-of-24 for 220 yards and four touchdowns, while Melvin Gordon held down the running game with 24 carries for 102 yards and a TD. Travis Benjamin was San Diego’s big receiver, with six receptions for 115 yards and two touchdowns. On the Chargers season, Rivers has bagged 463 yards with five touchdowns, and Benjamin has the most, catching 13 of his 14 targets for 147 yards and the two touchdowns. Gordon has put up 38 carries for 159 yards, but his fellow RB Danny Woodhead was injured in Week 2 and will be out for the season. 

Moving on over to the Colts, they’re coming off another loss in Week 2, making them 0-2 on the year so far. This most recent defeat came at the hands of the Broncos, with Indy going down 34-20. The Colts were in the game and threatening to take the lead when Denver’s Vonn Miller strip-sacked Indianapolis QB Andrew Luck, leading to the decisive Broncos TD. In that game, Luck finished 21-of-40 with 197 yards, a TD and an interception. T.Y. Hilton led the Colts with four receptions for just 41 yards, while Frank Gore didn’t have much better luck on the ground with 13 carries for 44 yards. Through two games, Luck holds 582 yards with five touchdowns, while Phillip Dorsett leads Indianapolis in receiving yards with 124. Gore has managed 103 yards on 27 carries, and hasn’t yet found the end zone. 

The Chargers a 4-0 ATS against a team with a losing record, and 7-0 ATS in their last seven road games. San Diego is also 6-0 ATS in their last six games overall, and 13-3-1 ATS in their last 17 September games. 

Meanwhile, the Colts are 5-2 ATS in their last seven Week 3 games, and 21-9 ATS in their last 30 games following a straight-up loss. Indianapolis is also 25-11-1 ATS in their last 37 home games, and 3-7 ATS in their last 10 games following an ATS loss. 

The Colts defense is a little on the slow side and usually has trouble covering receivers out of the backfield. With Woodhead out, that will play to Indianapolis’ advantage. I’ll take the Colts to eke out a close victory here.

Indianapolis Colts -3.5

Andrew has been with Sports Chat Place since 2012, contributing to football, baseball and basketball across the fantasy, college and professional ranks. His goal is to break down the complicated trends and numbers into a language that's accessible even if you're not a seasoned sports bettor, providing comprehensive insight that can apply to just about everyone. Follow Andrew on Twitter for links to his latest Sports Chat Place picks. 

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