Arizona Cardinals vs San Francisco 49ers prediction 12-17-23 NFL Picks

The San Francisco 49ers and the Arizona Cardinals meet in a week 15 NFC West matchup in NHL action from State Farm Stadium on Sunday afternoon. First meets worst in the division on Sunday, who comes out on top? Let’s take a look and give out a 49ers vs. Cardinals Prediction.

San Francisco 49ers Team Preview

The San Francisco 49ers come into this game looking to build on their 10-3 mark this season following a 28-16 win over Seattle last time out. Brock Purdy has thrown for 3,553 yards, 25 touchdowns and 7 interceptions on 70.2% passing while Christian McCaffrey has a team-high 1,177 rushing yards and 12 touchdowns. Brandon Aiyuk has a team-high 1,053 receiving yards and 56 receptions with 6 touchdowns while George Kittle has 53 grabs for 811 yards and 6 touchdowns. Deebo Samuel has 45 receptions for 739 receiving yards and 4 TDs while Christian McCaffrey has 52 receptions for 437 yards as well this season. On defense, Fred Warner has a team-high 107 total tackles and 4 interceptions while Nick Bosa has a team-high 9.5 sacks and Javon Hargrave has 6 sacks. Arik Armstead also has 5 sacks while Talanoa Hufanga also has 3 interceptions this season.


San Francisco 49ers Team Facts

Arizona Cardinals Team Preview

The Arizona Cardinals come into this one looking to build on a 24-10 win over Pittsburgh last time out prior to their bye week. Kyler Murray has thrown for 864 yards, 3 touchdowns and 2 interceptions on 60.8% passing. James Conner leads the Cardinals in rushing with 631 rushing yards with 4 TDs as well. Trey McBride leads the Cardinals in receiving with 56 grabs for 610 yards while Marquise Brown has 51 receptions for 574 yards and 4 TDs and Michael Wilson has 28 catches for 435 yards and 2 scores. On defense, Kyzir White has a team-high 90 total tackles while Dennis Gardeck has a team-high 5 sacks and Jalen Thompson has 3 interceptions as well on the year.

Arizona Cardinals Team Facts

Matchup/League Facts

49ers vs. Cardinals Prediction

It’s a thick line here, but it’s 49ers or pass for me here. Now that San Francisco is back to being fully healthy, this team looks borderline unstoppable and are looking like the clear cut favorite to make it out of the NFC. Arizona got a nice win over Pittsburgh and are rested and prepared for this game, but the Niners are just on another level right now. Give me San Francisco laying the points.

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