Louisville vs Jackson State Prediction 11/6/25 College Basketball Picks Today

The Jackson State Tigers and the Louisville Cardinals meet Thursday in college basketball action from the KFC Yum! Center. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Jackson State Tigers vs. Louisville Cardinals prediction.

Jackson State Tigers Recap

The Jackson State Tigers come into this game looking to rebound from a 113-55 loss at the hands of Illinois last time out to sit at 0-1 on the year.

Tigers Looking For Massive Upset For First Win

Devin Ree led the Tigers with 19 points on 7 of 11 shooting with 4 threes and a pair of steals while Daeshun Ruffin added 12 points with 5 rebounds as the only other double-digit scorer for Jackson State so far this season. Mike Williams added 9 points with a pair of steals while Dorian McMillian added a team-high 3 assists and a pair of steals despite shooting 0 for 9 from the floor. 

Why the Jackson State Tigers will win

Louisville Cardinals Recap

The Louisville Cardinals come into this game looking to add on to their 104-45 blowout win over South Carolina State last time out to sit at 1-0 this season.

Cardinals Looking For Another Confident Win

Khani Rooths led the Cardinals with 20 points including 7 rebounds and 3 assists while Isaac McKneely added 17 points with 4 rebounds on 6 of 13 shooting with 5 threes. J’Vonne Hadley added 13 points with a team-high 9 rebounds and a pair of steals while Ryan Conwell added 12 points iwth 3 rebounds, 2 assists and 2 steals. Mikel Brown added 11 points on 4 of 6 shooting with a team-high 6 assists to cap off Louisville’s scoring in double figures in the win while Sananda Fru chipped in 9 points with a team-high 8 rebounds as well for the Cardinals as well in the win.

Why the Louisville Cardinals will win

Total Points Facts

Jackson State Tigers vs. Louisville Cardinals Prediction

I’m on Louisville here. I get the case to be made from either side in this game just given the size of this number, but I think that the Cardinals are still the better team by a mile and a half in this game. It’s just a matter of Louisville naming their number in this spot. The Cardinals run away with this one here. Give me Louisville.

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