Cardinals vs Astros Prediction 4/14/25 MLB Picks Today

In this article, we will formulate a Cardinals vs Astros prediction for this MLB game on Monday, April 14th at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 7-8 this year after they won two out of three against the Phillies by scores of 2-0, 1-4, and 7-0. In that game three win, the Cardinals were held scoreless through three innings, but they scored seven runs in the last five innings for the shutout win. The Cardinals recorded 10 hits in the game, and they were led by Contreras and Walker, who both had two RBIs in the win. St. Louis started Liberatore, who allowed just three hits over 6.0 innings for the win, while Maton, Romero, and Leahy threw three scoreless innings out of the bullpen. 

Prior to that series, the Cardinals lost two out of three against the Pirates and were swept by the Red Sox in three games. The St. Louis pitching staff has a 4.48 ERA with a 1.20 WHIP and a .226 opponent batting average, while their offense has scored 82 runs with a .280 batting average and a .350 on-base percentage this season. Brendan Donovan has led St. Louis with two home runs and 10 RBIs, while Nolan Arenado has added one home run and seven RBIs this year. The projected starting pitcher for St. Louis is Sonny Gray, who is 2-0 with a 4.50 ERA and a 0.88 WHIP over 16.0 innings pitched this year. 

Houston Astros Betting Preview

The Houston Astros are 7-8 this season after they won two out of three against the Angels by scores of 14-3, 1-4, and 7-3. In the 7-3 win on Sunday, Houston fell behind 2-0 in the second inning, but they scored seven of the last eight runs in the game for the win. The Astros recorded six hits in the game, and they were led by Paredes, who went 1-4 with one home run and three RBIs in the win. Houston started Wesneski, who allowed five hits and three earned runs over 6.0 innings in the win, while King, Abreu, and Hader finished the last three. 

Prior to that series, the Astros lost two out of three games against the Mariners and won two out of three against the Twins. The Houston pitching staff has a 3.69 ERA with a 1.06 WHIP and a .190 opponent batting average, while their offense has scored 60 runs with a .219 batting average and a .309 on-base percentage this season. Isaac Paredes has led Houston with three home runs and nine RBIs, while Jose Altuve has added three home runs and seven RBIs this year. The projected starting pitcher for Houston is Framber Valdez, who is 1-1 with a 2.50 ERA and a 0.94 WHIP over 18.0 innings pitched this season. 

Why the Cardinals will beat the Astros

Total Runs Facts

St. Louis Cardinals Player Prop Facts

Houston Astros Player Prop Facts

Matchup/League Facts

Cardinals vs Astros Prediction 

Both of these teams come into this series with a 7-8 record through 15 games, and each team is coming off of a series win. St. Louis did a better job of pitching against the Phillies, but they have struggled in that department this year. Houston has scored at least six runs in three of their last four games, so it will be interesting to see if they can capitalize against this St. Louis pitching staff. Both of these pitchers are very good, but I have to give the advantage to St. Louis and their high-scoring offense. Take the Cardinals here. 

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