Cubs vs Mariners Prediction 8/22/26 MLB Picks Today

In this article, we will formulate a Cubs vs Mariners Prediction for this MLB matchup on Saturday, August 22nd in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Seattle Mariners Preview

The Seattle Mariners have a 61-68 record this season and are sitting in the 3rd place of the AL West. They have a 34-29 home record and are coming off a 6-5 home win against the Cubs. They will face the Phillies and the Blue Jays next.

The Seattle Mariners have a .229 batting average this season, .309 OBP and .375 Slugging percentage. Seattle’s pitching staff has a 4.01 ERA and 1.23 WHIP. Randy Arozarena is the Mariners’ best hitter with a .271 batting average. Cole Young leads the team in RBI with 56, while Julio Rodriguez adds a team-high 19 home runs.

Kade Anderson is the projected starting pitcher for the Mariners and he will make his MLB debut today. Anderson has a 10-1 record and 1.06 ERA in 18 starts for Double-A Arkansas, striking out 135 batters and walking 13 across 93⅓ innings.

Chicago Cubs Preview

The Chicago Cubs have a 74-55 record this season and are sitting in the 2nd place of the NL Central. They have a 36-28 road record and are coming off a 5-6 road loss against the Mariners. They will face the Diamondbacks and the Reds next.

The Chicago Cubs have a .248 batting average this season, .337 OBP and .420 Slugging percentage. Chicago’s pitching staff has a 4.14 ERA and 1.26 WHIP. Pete Crow-Armstrong is the Cubs’ best hitter with a .279 batting average, while also leading the team in RBI with 80 and adding a team-high 32 home runs.

David Peterson (L) is the projected starting pitcher for the Cubs, and he has a 7-7 record, 5.29 ERA and 1.53 WHIP.

The Chicago Cubs @ Seattle Mariners Betting Trends: August 22, 2026

 

Why the Seattle Mariners will win

 

Why the Chicago Cubs will win

Total Runs Facts

Seattle Mariners Player Prop Facts

Chicago Cubs Player Prop Facts

Matchup/League Facts

Cubs vs Mariners Prediction

The Mariners are 3-1 in their last 4 meetings against the Cubs but have lost two of their last three meetings in Seattle.

In this Cubs vs Mariners Prediction, the Mariners are coming as -115 home favorites. I like the Cubs in this one, as Peterson has been in very good form, having given up two runs or less in six of his last seven starts and has been better on the road. Kade Anderson looked excellent in triple A, but he will face the second-best offense in baseball in his debut and the Mariners’ bullpen has been terrible lately. Take the Cubs to win this one.

 

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