Marlins vs Cardinals Prediction 4/21/26 MLB Picks Today

In this article we will formulate a Marlins vs Cardinals prediction for this MLB game on Tuesday, April 21st at loanDepot park in Miami, Florida. Let’s take a look at the prediction for this MLB matchup. 

Miami Marlins Betting Preview

The Miami Marlins are 11-12 this year after they won game one by a score of 5-3 on Monday night. Miami was tied at two in the sixth inning, but they scored two runs in the sixth and added another in the eighth for the win. The Marlins recorded six hits in the game and they were led by Hicks, who went 2-4 with two RBIs. Meyer allowed three hits and two earned runs over 5.1 innings, while Faucher picked up the win and Fairbanks got the save. Prior to this series, Miami lost two out of three against the Brewers and two out of three against the Braves. 

This season, Miami has a 4.01 ERA with a 1.25 WHIP and a .216 opponent batting average, while they have scored 105 runs with a .254 batting average and a .330 on base percentage. Liam Hicks has led the Marlins with four home runs and 21 RBIs, while Owen Caissie has added two home runs and 13 RBIs. The projected starting pitcher for Miami is Chris Paddack, who is 0-3 with a 5.59 ERA and a 1.45 WHIP over 19.1 innings pitched this year. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 13-9 this season after they lost game one by a score of 5-3 on Monday night. St. Louis led 1-0 in the fourth and they were tied at two in the sixth, but didn’t score again until the ninth for the loss. The Cardinals recorded five hits in the game and they were led by Winn and Urias, who both had one RBI. McGreevy allowed five hits and four earned runs over 5.2 innings for the loss, while Fernandez allowed one earned run in relief. Prior to this series, St. Louis swept the Astros in three games and won two out of three against the Guardians. 

This season, St. Louis has a 4.83 ERA with a 1.41 WHIP and a .255 opponent batting average, while they have scored 103 runs with a .233 batting average and a .328 on base percentage. Jordan Walker has led the Cardinals with eight home runs and 16 RBIs, while Alec Burleson has added three home runs and 15 RBIs. The projected starting pitcher for St. Louis is Dustin May, who is 2-2 with a 6.98 ERA and a 1.60 WHIP over 19.1 innings pitched this season. 

Why the Miami Marlins will win

Why the St. Louis Cardinals will win

Total Runs Facts

Miami Marlins Player Prop Facts

St. Louis Cardinals Player Prop Facts

Matchup/League Facts

Marlins vs Cardinals Prediction 

St. Louis had their winning streak snapped on Monday night, but they have scored at least five runs in four of their last five games. The Cardinals are 6-4 on the road this year, while the Marlins are 9-5 at home. Miami has won two in a row and they have scored five runs in three of their last four. The Marlins are starting Paddack, who has allowed two earned runs or fewer in three straight starts, while May has allowed 1, 1, 7, and 6 earned runs in his four outings. I don’t trust either starter in this game, but Paddack has at least put together three decent starts. Take the Marlins at home. 

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