Orioles vs Astros Prediction 4/28/26 MLB Picks Today

In this article we will formulate an Orioles vs Astros prediction for this MLB game on Tuesday, April 28th at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 13-15 this season after they lost two out of three against the Red Sox by scores of 10-3, 1-17, and 3-5. In game three, Baltimore cut the deficit to 5-3 in the eighth inning, but couldn’t get any closer in the loss. The Orioles recorded six hits and they committed one error, while they were led by Henderson, who went 2-4 with one home run and two RBIs in the game. Bradish allowed four hits and three earned runs over 5.0 innings for the loss, while Wolfram allowed two earned runs in relief. Prior to that series, Baltimore won two out of three against the Royals, but lost three out of four against the Guardians before that. 

This season, Baltimore has a 4.33 ERA with a 1.39 WHIP and a .258 opponent batting average, while they have scored 125 runs with a .238 batting average and a .321 on base percentage. Gunnar Henderson has led the Orioles with nine home runs and 18 RBIs, while Jeremiah Jackson has added five home runs and 19 RBIs. The projected starting pitcher for Baltimore is Shane Baz, who is 0-2 with a 5.08 ERA and a 1.55 WHIP over 28.1 innings pitched this season. 

Houston Astros Betting Preview

The Houston Astros are 11-18 this year after they lost two out of three against the Yankees by scores of 4-12, 3-8, and 7-4. In game three, Houston scored the first seven runs in the game and they were able to hang on for the win. The Astros recorded seven hits in the game and they were led by Walker, who went 3-4 with one home run and four RBIs. Arrighetti allowed three hits and one earned run over 7.0 innings for the win, while De Los Santos allowed three earned runs in relief. Prior to that series, Houston won two out of three against the Guardians, but lost all three against the Cardinals before that. 

This season, Houston has a 5.97 ERA with a 1.65 WHIP and a .267 opponent batting average, while they have scored 151 runs with a .259 batting average and a .345 on base percentage. Yordan Alvarez has led the Astros with 11 home runs and 26 RBIs, while Christian Walker has added seven home runs and 23 RBIs. The projected starting pitcher for Houston is Kai-Wei Teng, who is 1-1 with a 2.16 ERA and a 0.90 WHIP over 16.2 innings pitched this year. 

Why the Baltimore Orioles will win

Why the Houston Astros will win

Total Runs Facts

Baltimore Orioles Player Prop Facts

Houston Astros Player Prop Facts

Orioles vs Astros Prediction 

Both of these teams come into this matchup after losing their last series, but Houston has the worst team ERA in the MLB. The Astros are 3-10 on the road this year, while the Orioles are 7-8 at home. Baltimore has allowed 22 runs in their last two games, but they have also scored 5+ runs in three of their last five. The O’s are starting Baz, who has allowed four earned runs in three of his five starts, while Teng will act as an opener. I don’t trust this Houston pitching staff at all, so take the over here. 

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