Rays vs Red Sox Prediction 4/16/25 MLB Picks Today

In this article, we will formulate a Rays vs Red Sox prediction for this MLB game on Wednesday, April 16th at George M. Steinbrenner Field in Tampa, Florida. Let’s take a look at the prediction for this MLB matchup. 

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 8-9 this season, and they have won three of their last five games. Tampa Bay won game one in this series by a score of 16-1 on Monday, but they lost game two by a score of 7-4. In that loss, the Rays cut the deficit to 3-1 in the second inning, but their pitching couldn’t hold up, and they were out of it for most of the game. Tampa Bay recorded seven hits in the game, and they were led by Diaz, Aranda, Misner, and Walls, who all had one RBI in the game. Tampa Bay started Pepiot, who allowed nine hits and six earned runs in the loss, while Bigge allowed one earned run and one hit in a relief inning. 

Prior to this series, the Rays won two out of three against the Braves and lost two out of three against the Angels. The Tampa Bay pitching staff has a 3.58 ERA with a 1.13 WHIP and a .232 opponent batting average, while the offense has scored 81 runs with a .272 batting average and a .336 on-base percentage this season. Brandon Lowe has led Tampa Bay with three home runs and 11 RBIs, while Jonathan Aranda has also added three home runs and 11 RBIs for the Rays this year. The projected starting pitcher for Tampa Bay is Zack Littell, who is 0-3 with a 6.88 ERA and a 1.24 WHIP over 17.0 innings pitched this season. 

Boston Red Sox Betting Preview

The Boston Red Sox are 9-10 this year, and they have lost six of their last nine games. In their game two win on Tuesday night, Boston scored seven of the first nine runs in the game, and they were able to coast until the ninth, when Tampa Bay applied a little pressure. The Red Sox recorded 12 hits in the game, and they were led by Bregman, who went 5-5 with two home runs and four RBIs in the win. Boston started Buehler, who allowed three hits and two earned runs over 5.0 innings for the win, while Chapman pitched the final out for the save. 

Prior to this series, the Red Sox lost two out of three against the White Sox and three out of four against the Blue Jays. The Boston pitching staff has a 4.38 ERA with a 1.35 WHIP and a .265 opponent batting average, while their offense has scored 85 runs with a .251 batting average and a .323 on-base percentage this season. Alex Bregman has led Boston with four home runs and 16 RBIs, while Wilyer Abreu has added three home runs and 12 RBIs this year. The projected starting pitcher for Boston is Sean Newcomb, who is 0-2 with a 4.97 ERA and a 2.13 WHIP over 12.2 innings pitched this season. 

Why the Rays will beat the Red Sox

Total Runs Facts

Tampa Bay Rays Player Prop Facts

Boston Red Sox Player Prop Facts

Rays vs Red Sox Prediction 

Both of these teams come into this matchup below .500 on the season, but each side has a chance at a big series win here. The Red Sox finally scored some runs on Tuesday, but their offense has really struggled. Tampa Bay has scored 28 runs in its last three games and will face Newcomb, who has allowed a ton of baserunners so far this year. I really don’t love the pitching matchup here, but I have very little faith in the Boston bats right now. Take the Rays to win. 

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