Toronto Blue Jays vs Houston Astros Prediction 9/10/25 MLB Picks Today

The Houston Astros and the Toronto Blue Jays meet Wednesday in MLB action from Rogers Centre. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Houston Astros vs. Toronto Blue Jays prediction.

Starting Pitching Matchup

The Houston Astros will send out Jason Alexander for the start here and Alexander is 4-1 with a 4.68 ERA and 52 strikeouts this season. This will be Alexander’s first career start against the Blue Jays. Jose Berrios will get the nod for the Blue Jays here and is 9-5 with a 4.02 ERA and 131 strikeouts this season. In his last five starts against the Astros, Berrios is 3-1 with a 3.34 ERA and 13 strikeouts.

Houston Astros Recap

The Houston Astros come into this game looking to bounce back from a 4-3 loss at the hands of the Blue Jays in Tuesday’s matchup to sit at 78-67 on the year. After this series, the Astros will head on the road for a series against the Atlanta Braves.

Astros Drop 7 Of Last 10

Jose Altuve has 142 hits including 22 doubles, 24 home runs and 69 RBIs. Jeremy Pena also has 137 hits with 26 doubles, 15 homers and 54 RBIs with 20 stolen bases as well. Jake Meyers has 15 doubles as well and Christian Walker has 22 home runs and 76 RBIs but has also accrued a team-high 156 strikeouts so far this season. Altuve also has 9 stolen bases while Jake Meyers has 15 stolen bases this season. Isaac Paredes also has 19 home runs with 50 RBIs of his own and Cam Smith has contributed 8 homers and 49 RBIs. Yainer Diaz has also chipped in 120 hits with 18 home runs, 60 RBIs and 20 doubles.

Why the Houston Astros will win

Houston Astros Player Prop Facts

Toronto Blue Jays Recap

The Toronto Blue Jays come into this game looking to add on to their win over the Astros from Tuesday’s matchup to sit at 83-61 this season. After this series, the Blue Jays will take on the Baltimore Orioles in a series at home.

Blue Jays Looking To Create Distance In Division

George Springer has 127 hits and Bo Bichette has 181 hits with Springer adding 27 home runs, a triple, 21 doubles and 72 RBIs while Bichette has 44 doubles, 18 home runs and 93 RBIs. Andres Gimenez has added 60 hits with 8 doubles and 7 home runs and 27 RBIs this season along with 12 stolen bases. Vladimir Guerrero Jr. also has 23 homers, 33 doubles and 79 RBIs while Springer also has a .301 batting average and 91 strikeouts up to this point in the year. Addison Barger’s chipped in 27 doubles with 19 home runs and 65 RBIs and Ernie Clement’s added 28 doubles as part of his 132 hits this season.

Why the Toronto Blue Jays will win

Toronto Blue Jays Player Prop Facts

Total Runs Facts

Houston Astros vs. Toronto Blue Jays Prediction

I’m on the Blue Jays here. I get the case to be made for Houston, but the Blue Jays have a ton of momentum after walking off Houston on Tuesday and I think the Blue Jays can pick up another win here. The Astros have been struggling to put it all together and have been stumbling as of late and I think Toronto takes advantage of that here. Give me the Blue Jays in this one.

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