Orioles vs Cardinals Prediction 5/27/25 MLB Picks Today

In this article, we will formulate an Orioles vs Cardinals prediction for this MLB game on Tuesday, May 27th at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 19-34 this year after they won game one by a score of 5-2 on Monday afternoon. Baltimore scored the first five runs in the game, but they failed to score in the final four innings in the win. The Orioles recorded 10 hits and they committed one error in the game, while they were led by Carlson, who went 2-4 with one home run and three RBIs in the win. Baltimore started Morton, who allowed four hits and two earned runs over 6.0 innings for the win, while Bautista picked up the save. 

Prior to this series, the Orioles split four games with the Red Sox, but lost two out of three against the Brewers before that. Baltimore has won three games in a row, and they are currently last in the AL East standings. The Baltimore pitching staff has a 5.45 ERA with a 1.47 WHIP and a .272 opponent batting average, while their offense has scored 205 runs with a .236 batting average and a .303 on-base percentage this season. Cedric Mullins has led Baltimore with 10 home runs and 31 RBIs, while Ryan O’Hearn has added eight home runs and 18 RBIs this year. The projected starting pitcher for Baltimore is Tomoyuki Sugano, who is 4-3 with a 3.07 ERA and a 1.02 WHIP over 58.2 innings pitched this year. 

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 30-24 this season after they lost game one in this series on Monday. St. Louis cut the deficit to 5-2 in the fifth inning, but couldn’t get anything else going in the loss. The Cardinals recorded four hits and they committed two errors in the game, while they were led by Pages, who went 1-3 with one home run and two RBIs in the loss. St. Louis started Fedde, who allowed seven hits and three earned runs over 5.0 innings for the loss, while Svanson, King, and Graceffo finished the final three innings. 

Prior to this series, the Cardinals swept the Diamondbacks in three games, but lost two out of three against the Tigers before that. St. Louis has won three of their last four games, and they are currently second in the NL Central standings. The St. Louis pitching staff has a 3.72 ERA with a 1.22 WHIP and a .240 opponent batting average, while their offense has scored 256 runs with a .259 batting average and a .330 on-base percentage this season. Wilson Contreras has led St. Louis with six home runs, 28 RBIs, and two stolen bases, while Lars Nootbaar has added seven home runs and 25 RBIs this year. The projected starting pitcher for St. Louis is Andre Pallante, who is 4-3 with a 4.18 ERA and a 1.34 WHIP over 56.0 innings pitched this season. 

Why the Orioles will beat the Cardinals

Total Runs Facts

Baltimore Orioles Player Prop Facts

St. Louis Cardinals Player Prop Facts

Orioles vs Cardinals Prediction 

Baltimore was able to get a win on Monday afternoon in game one of this series, and they have won three games in a row. The Orioles are 9-15 at home this year, while the Cardinals are 11-16 on the road. St. Louis has been a bit inconsistent in their last six games, and they are starting Pallante, who has allowed two earned runs or fewer in two of his last three starts. The O’s are going with Sugano, who has allowed two earned runs or fewer in four of his last five. Baltimore has some momentum for the first time this season, and Sugano has been very good, so I like the Orioles to win here. 

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