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Boston Red Sox vs Minnesota Twins Prediction 9-22-24 MLB Picks

Minnesota Twins (81-73) vs. Boston Red Sox (76-77)
September 22, 2024 12:35 pm EDT
The Line: Boston Red Sox -111 / Minnesota Twins -106; Over/Under: +8.5
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In this article, we will formulate a Boston Red Sox vs Minnesota Twins prediction for this MLB game on Sunday, September 22nd at Fenway Park in Boston, Massachusetts. To formulate this prediction for the doubleheader, we will examine:

  • The Twins’ recent form and recent player performance 
  • The Red Sox’s recent form and recent play performance
  • Recent Betting trends and streaks involving Minnesota
  • Recent Betting trends and streaks involving Boston
  • Recent betting trends in games played between Minnesota and Boston
  • A summary that ties it all together and produces a favorable betting outcome for Today’s Game between Minnesota and Boston

Minnesota Twins Betting Preview

The Minnesota Twins are 81-73 this year and they have lost two of their last three games. Minnesota was able to get the win in game one of this series by a score of 4-2 in extra innings. Prior to this series, the Twins lost three out of four against the Guardians, lost two out of three against the Reds, and won two out of three against the Angels. Minnesota is 3-5 in their last eight games and they are third in the AL Central. 


The Minnesota pitching staff has a 4.16 ERA, a 1.20 WHIP, and a .239 opponent batting average. The Twins’ offense has scored 717 runs with a .248 batting average and a .317 on-base percentage. Carlos Santana is batting .238 with 22 home runs and 65 RBI’s for the Twins this season. 

Boston Red Sox Betting Preview

The Boston Red Sox are 76-78 this season and they have lost four of their last five games. Boston dropped game one in this series in extra innings, as they were just 1-19 with runners in scoring position. Prior to this series, the Red Sox lost two out of three against the Rays, lost three out of four against the Yankees, and won two out of three against the Orioles. Boston is 4-8 in their last 12 games and they are third in the AL East. 

The Boston pitching staff has a 4.09 ERA, a 1.26 WHIP, and a .247 opponent batting average. The Red Sox offense has scored 717 runs with a .252 batting average and a .318 on-base percentage. Jarren Duran is batting .285 with 21 home runs and 73 RBI’s for the Red Sox this season. 

Starting Pitchers

The projected starting pitcher for Minnesota in game one is Pablo Lopez, who is 15-8 with a 3.84 ERA and a 1.15 WHIP over 175.2 innings pitched this year. Lopez has allowed two earned runs or fewer in four of his last five starts. The projected starting pitcher for the Twins in game two is Zebby Matthews, who is 1-3 with a 6.30 ERA and a 1.60 WHIP over 30.0 innings pitched this year. Matthews has allowed at least four earned runs in two of his last four starts.

The projected starting pitcher for Boston in game one is Nick Pivetta, who is 5-11 with a 4.37 ERA and a 1.13 WHIP over 134.0 innings pitched this year. Pivetta has allowed two earned runs or fewer in three of his last four starts. The projected starting pitcher for game two for Boston is Kutter Crawford, who is 8-15 with a 4.19 ERA and a 1.10 WHIP over 171.2 innings pitched this season. Crawford has allowed two earned runs or fewer in three of his last five starts but has allowed seven earned runs in his last two outings. 

Why the Red Sox will beat the Twins

  • The Red Sox have won each of their last nine home games against the Twins following a home loss.
  • The Twins have lost each of their last five games following a road win.
  • The Twins have failed to cover the run line in 10 of their last 11-day games against AL East opponents that held a losing record.
  • The Red Sox have covered the run line in seven of their last eight home games against the Twins following a home loss.
  • The Red Sox have led after 5 innings in each of their last five-day games at Fenway Park against AL Central opponents.

Why the Twins will beat the Red Sox

  • The Red Sox have lost eight of their last nine-day games following an extra innings loss.
  • The Twins have won five of their last six games against the Red Sox.
  • The Red Sox have failed to cover the run line in each of their last eight Sunday games against teams that held a winning record.
  • The Twins have covered the run line in eight of their last nine-day games following an extra-innings win.
  • The Red Sox have trailed after 5 innings in each of their last five Sunday games against American League opponents that held a winning record.

Total Runs Facts

  • Each of the Red Sox’s last seven-day games against American League opponents has gone UNDER the total runs line.
  • Each of the Twins’ last four games following an extra innings win has gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Red Sox’s last seven games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Twins’ last four games against AL East opponents.

Boston Red Sox Player Prop Facts

  • Rafael Devers has hit a home run in three of the Red Sox’s last four-day games against AL Central opponents that held a winning record.
  • Connor Wong has recorded an RBI in each of the Red Sox’s last three games against AL Central opponents.
  • Tyler O’Neill has scored at least one run in each of his last six home appearances against opponents that held a winning record.
  • Ceddanne Rafaela has recorded at least one hit in each of the Red Sox’s last 13 home games against AL opponents that held a winning record.
  • Ceddanne Rafaela has recorded at least one Single in 11 of the Red Sox’s last 12 home games against AL opponents that held a winning record.
  • Nick Pivetta has recorded seven or more strikeouts in nine of his last 10 home appearances against AL opponents.
  • Masataka Yoshida has recorded a Double in four of his last five home appearances against opponents that held a winning record.
  • Ceddanne Rafaela has recorded at least one total base in each of the Red Sox’s last 13 home games against AL opponents that held a winning record.

Minnesota Twins Player Prop Facts

  • Byron Buxton has recorded a Double in each of his last five appearances in day games against AL teams that held a losing record.
  • Carlos Correa has recorded at least one total base in each of his last 11 appearances against opponents that held a losing record.
  • Byron Buxton has scored at least one run in nine of his last 10 appearances in day games against teams that held a losing record.
  • Pablo Lopez has recorded a win in four of his last five appearances.
  • Carlos Santana has hit a home run in five of the Twins’ last eight road games against AL East opponents that held a losing record.
  • Manuel Margot has recorded at least one RBI in four of his last five road appearances against the Red Sox.
  • Carlos Correa has recorded at least one hit in each of his last 11 appearances against opponents that held a losing record.
  • Carlos Santana has recorded a Single in each of his last seven appearances against opponents that held a losing record.

Boston Red Sox vs Minnesota Twins Prediction 

Minnesota was able to get a huge win in the first game of this series on Friday night and they will look to string some wins together here. The Twins are battling the Tigers for the last wild card spot in the AL and they haven’t played very well recently, so this is a huge series. I like Pablo Lopez to have another strong start here, as he has been great, so I like the Twins in game one. In game two, I am going to side with the Red Sox, as I don’t trust Matthews on the mound for Minnesota. 

David Racey's Free Pick: Twins ML and Red Sox ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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