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Buffalo Bills vs Kansas City Chiefs Prediction 11-17-24 NFL Picks

Kansas City Chiefs (9-0) vs. Buffalo Bills (8-2)
November 17, 2024 4:25 pm EDT
The Line: Buffalo Bills -2.5; Over/Under: +45.5
(Get latest betting odds)

The Kansas City Chiefs and the Buffalo Bills will meet Sunday in NFL action from Bills Stadium. Here’s a Buffalo Bills vs Kansas City Chiefs prediction. We will look at this from a betting perspective and determine the best Bills vs Chiefs pick.

Kansas City Chiefs Betting Preview

The Chiefs have been on a great run so far this year, managing to stay undefeated despite some very close calls. Kansas City has taken out the Ravens, Bengals, Falcons, Chargers, Saints, 49ers, Raiders, Buccaneers and Broncos in succession so far.


In the Broncos matchup on Sunday, the Chiefs gave up 14 points in the second quarter but clawed back on a pair of second-half field goals for a 16-14 victory. Patrick Mahomes threw for 266 yards and a score. Kareem Hunt added six catches for 65 yards as the lead receiver.

Buffalo Bills Betting Preview

Over on the Bills’ side, they’ve had a pretty good season themselves. Buffalo lost consecutive games to the Ravens and Texans in late September/early October. Aside from that, it’s been wins over the Cardinals, Dolphins, Jaguars, Jets, Titans, Seahawks, Dolphins and Colts in succession.

In the Colts game, the Bills took a 20-13 edge into the second half. After 10 fourth-quarter points, Buffalo walked away with a 30-20 win. Josh Allen threw for 280 yards and two interceptions with a rush score. James Cook bagged 19 carries for 80 yards on the ground.

Total Points Facts

  • Each of the Bills’ last seven games played as favorites on the East Coast have gone OVER the total points line.
  • Each of the last five Sunday games at Highmark Stadium has gone OVER the total points line.
  • Each of the Chiefs’ last four road games against AFC East opponents has gone OVER the total points line.

Buffalo Bills Player Prop Facts

  • Josh Allen has scored at least one touchdown in each of the Bills’ last four games against AFC West opponents.
  • Josh Allen has recorded 32+ rushing yards in each of the Bills’ last seven games against the Chiefs.
  • Curtis Samuel has recorded 32+ rushing and receiving yards in five of his six previous appearances against AFC West opponents.
  • Josh Allen has recorded 232+ passing yards in each of the Bills’ last six Sunday regular season games as favorites.
  • Dawson Knox has recorded 17+ receiving yards in eight of his last nine November appearances.
  • Josh Allen has recorded 23+ completions in each of the Bills’ last four games against the Chiefs.
  • Josh Allen has thrown two or more touchdowns in seven of the Bills’ last eight games played as favorites on the East Coast.
  • Rasul Douglas is just one away from 20 career interceptions.

Kansas City Chiefs Player Prop Facts

  • Patrick Mahomes has recorded 256+ passing yards in each of his six previous regular-season appearances with the Chiefs as road underdogs against AFC opponents.
  • DeAndre Hopkins has recorded 51+ receiving yards in each of his last nine Week 11 appearances.
  • Patrick Mahomes has recorded 19+ rushing yards in seven of the Chiefs’ last eight games as slight underdogs (<+3.5 points).
  • Samaje Perine has recorded 35+ rushing and receiving yards in each of his last eight November appearances.
  • Travis Kelce has scored at least one touchdown in each of the Chiefs’ last six Week 11 games.
  • Kareem Hunt has scored the first touchdown in three of his last four road appearances.
  • Patrick Mahomes has thrown four or more touchdowns in four of his last five regular-season appearances with the Chiefs as road underdogs against AFC opponents.
  • Patrick Mahomes has recorded 23+ completions in seven of his last eight regular-season appearances with the Chiefs as road underdogs.
  • Justin Reid is just one away from 10 career interceptions.

Buffalo Bills vs Kansas City Chiefs Prediction

I’ll go with Buffalo here. We should have a pretty fun matchup, though. The Bills defense did most of the work in their latest win over the Colts, notching four takeaways (three picks) and 4-of-11 allowed on third-down conversions. The offense wasn’t exactly perfect with a couple of turnovers (not to mention eight team penalties total), but got the job done.

As for KC, they’re coming off yet another Houdini escape over a tricky Broncos team. The Chiefs held Denver to just 260 total yards (78 rushing) and 16 first downs. On offense, Kansas City notched 300 yards (243 passing) and 19 first downs. Sunday’s game should be a great matchup on both sides but ultimately I like the Bills to pull off the cover at home and give KC their first loss. It’ll be a great game to watch regardless.

Andrew's Free Pick: Buffalo Bills -2.5

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Andrew

Andrew has been writing about college, professional and fantasy sports betting since 2013. Andrew's goal is to break down the complicated numbers and trends into a language that's easily accessible to novice sports bettors and seasoned professionals alike.

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