Mariners vs Astros Prediction 4/7/25 MLB Picks Today

The Houston Astros and the Seattle Mariners meet Monday in MLB action from T-Mobile Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Houston Astros vs. Seattle Mariners prediction.

Starting Pitching Matchup

The Houston Astros will send out Hayden Wesneski for the start here and Wesneski is 0-1 with a 5.40 ERA and 6 strikeouts this season. This will be Wesneski’s second career start against the Mariners. Logan Gilbert will get the start for the Mariners here and is 0-1 with a 3.00 ERA and 18 strikeouts so far this season. In his last five starts against the Astros, Gilbert is 3-2 with a 3.00 ERA and 26 strikeouts.

Houston Astros Recap

The Houston Astros will look to build some steam after winning their series with the Minnesota Twins this past weekend, thanks to a 9-7 win in 10 innings in Sunday’s rubber match to improve to 4-5 on the year. After this series the Astros will head back home for a series with the Los Angeles Angels.

Astros Looking For Some Consistency Early On

Jose Altuve leads the Astros with 12 hits including a pair of solo home runs while also boasting a team-high 11 strikeouts. Jeremy Pena also has a pair of solo homers and a pair of stolen bases while Yordan Alvarez has a double and a team-high 4 RBIs with 11 strikeouts as well. Brendan Rodgers has a pair of doubles and 3 RBIs and Christian Walker has also accrued 11 strikeouts so far this season.

Why the Houston Astros will win

• The Astros have won each of their last eight night games against American League opponents following a win.
• The Mariners have lost four of their last five games as favorites.
• The Astros have covered the run line in each of their last eight road games against American League opponents after playing the previous day.
• The Mariners have failed to cover the run line in seven of their last eight games as home favorites after playing the previous day.

Houston Astros Player Prop Facts

• Brendan Rodgers has recorded a Double in three of his last four appearances with his team as a road underdog.
• Yordan Alvarez has hit a home run in four of the Astros’ last five road games against AL West opponents.
• Yordan Alvarez has recorded at least one RBI in four of the Astros’ last five road games against AL West opponents.
• Yordan Alvarez has scored at least one run in each of the Astros’ last six night games against AL West opponents that held a losing record.
• Jose Altuve has recorded at least one Single in each of his last nine appearances with the Astros as underdogs against the Mariners.
• Jose Altuve has recorded at least one hit in each of his last 12 road appearances against the Mariners after playing the previous day.
• Jose Altuve ranks T3rd in the league in Hits (14) this season.

Seattle Mariners Recap

The Seattle Mariners come into this one looking to rebound after being swept by the San Francisco Giants this past weekend thanks to a 5-4 loss in Sunday’s series finale to fall to 3-7 on the year. After this series the Mariners will welcome the Texas Rangers to town for another divisional series.

Mariners Drop Three In A Row

Jorge Polanco has 9 hits including a pair of home runs and 8 RBIs while Victor Robles has a team-high 12 hits with a team-high 3 doubles. Randy Arozarena has 5 hits with 3 doubles and a pair of home runs but also leads Seattle with 14 strikeouts as well on the year. Julio Rodriguez has chipped in 8 hits with 3 home runs and a triple and a team-high 3 stolen bases while Robles also has 3 SB and Cal Raleigh and Ryan Bliss have each added a pair of stolen bags as well on the year.

Why the Seattle Mariners will win

• The home team has won each of the Mariners’ last four games.
• The Astros have lost each of their last four games after going to extra innings.
• The Astros have failed to cover the run line in eight of their last nine games at T-Mobile Park against teams that held a losing record.
• The Mariners have covered the run line in each of their last four games against the Astros.

Seattle Mariners Player Prop Facts

• Cal Raleigh has hit a home run in four of the Mariners’ last five games against AL West opponents that held a losing record.
• J.P. Crawford has scored at least one run in each of the Mariners’ last six Monday games against AL West opponents that held a losing record.
• Cal Raleigh has recorded at least one RBI in each of his last nine Monday appearances against AL teams that held a losing record.
• Logan Gilbert has recorded seven or more strikeouts in each of his last nine appearances with the Mariners as favorites against AL opponents.
• Victor Robles has recorded a Double in three of the Mariners’ last four games against the Astros.
• Jorge Polanco has recorded at least one hit in each of his last nine appearances in night games.
• Jorge Polanco has recorded at least one Single in each of his last six appearances in night games against teams that held a losing record.
• Logan Gilbert ranks T3rd in the league for total Strikeouts (18) this season.

Total Runs Facts

• Each of the Astros’ last seven road games after going to extra innings have gone UNDER the total runs line.
• Six of the last seven games between the Astros and Mariners at T-Mobile Park have gone UNDER the total runs line.

Houston Astros vs. Seattle Mariners Prediction

I’m leaning towards Seattle here. I still have my concerns about the Mariners offense but this feels like a spot where the Mariners need Logan Gilbert to be their stopper and I think he can. The Astros had a nice rally to beat the Twins on Sunday, but I think that game was more about the Twins losing that game than it was about the Astros winning it and Houston’s still scored 3 runs or less in the majority of their games this season. I think the Mariners’ offense showed some life in that Giants series and if they can carry that over here I think the Mariners can start the series with a win here. Give me Seattle in this one.