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Pirates vs Nationals Prediction 4/14/25 MLB Picks Today

Washington Nationals (6-9) vs. Pittsburgh Pirates (5-11)
April 14, 2025 6:40 pm EDT
The Line: Pittsburgh Pirates -218 / Washington Nationals 180; Over/Under: 7
(Get latest betting odds)

The Washington Nationals and Pittsburgh Pirates meet on Monday in MLB action at PNC Park. Here’s a Pirates vs Nationals Prediction. This article will include a Pirates vs Nationals Pick.

Washington Nationals Betting Preview

The Washington Nationals are 6-9 on the year and play the Rockies, Orioles, and Mets next. The Washington Nationals are batting .239 on the season, have a .321 OBP, and a .404 slugging percentage. The Washington Nationals’ pitching staff has a 5.15 ERA and a 1.57 WHIP. Keibert Ruiz leads the Washington Nationals with 19 hits and 10 RBI, while James Wood and Nathaniel Lowe have combined for 27 hits and 26 RBI.


Brad Lord gets the ball for the Washington Nationals, and he is 0-0 with a 1.80 ERA and 4 strikeouts this season. This will be Lord’s first career game against the Pittsburgh Pirates.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 5-11 on the year and play the Guardians, Angels, and Dodgers next. The Pittsburgh Pirates are batting .184 on the season, have a .273 OBP, and a .290 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 4.40 ERA and a 1.30 WHIP. Bryan Reynolds leads the Pittsburgh Pirates with 13 hits and 6 RBI, while Isiah Kiner-Falefa and Ke’Bryan Hayes have combined for 24 hits and 9 RBI.

Paul Skenes gets the ball for the Pittsburgh Pirates, and he is 1-1 with a 3.44 ERA and 20 strikeouts this season. This will be Skenes’ first career game against the Washington Nationals.

Why the Pittsburgh Pirates will win

  • The Nationals have lost each of their last 15 night games following a road loss.
  • The Pirates have won seven of their last eight night games against NL East opponents.
  • The Pirates have covered the run line in seven of their last eight home games against NL East opponents following a loss.
  • The Nationals have failed to cover the run line in seven of their last eight night games against National League opponents following a road loss.
  • The Pirates have won the first inning in each of their last five home games against NL East opponents.
  • The Nationals have trailed after 3 innings in each of their last six night games against NL Central opponents that held a losing record.
  • The Nationals have trailed after 5 innings in each of their last six road night games.

Why the Washington Nationals will win

  • The underdogs have won each of the Pirates’ last four games at PNC Park.
  • The Pirates have lost four of their last five games as favorites against National League opponents.
  • The Nationals have covered the run line in each of their last nine Monday road games against National League opponents.
  • The Pirates have failed to cover the run line in seven of their last eight games as favorites.
  • The Pirates have trailed after 5 innings in five of their last six night games against opponents that held a losing record.
  • The Nationals have won the first inning in three of their last four night games against National League opponents that held a losing record.
  • The Nationals have led after 3 innings in six of their last seven games as underdogs against National League opponents.

Matchup/League Facts

  • The Pirates rank 30th in the league for batting average this season (.184).
  • The Pirates rank 30th in the league for slugging percentage this season (.290).
  • The Nationals rank 30th in the league for ERA this season (5.15).
  • The Nationals rank 29th in the league for opponent batting average this season (.279).

Pirates vs Nationals Prediction

The Pirates are going to be favored for obvious reasons, as they’re at home with one of the best pitchers in baseball. Skenes was fantastic last season as a rookie, and despite a slowish start to the season, you should expect him to get rolling with more reps under his belt. However, it doesn’t matter how great Skenes is if the Pirates can’t string together an offense.

The Pirates have scored a combined five runs in their last three games and three or fewer runs in five straight games. The Nationals have issues of their own, but they’ve had more success overall than the Pirates and have scored four or more runs in nine straight games. We’re getting almost two times our money to fade the Pirates. Skenes or not, I’ll take it.

Randy Chambers's Free Pick: Washington Nationals +180

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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