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White Sox vs Athletics Prediction 4/15/25 MLB Picks Today

Oakland Athletics (6-10) vs. Chicago White Sox (4-11)
April 15, 2025 7:40 pm EDT
The Line: Chicago White Sox 140 / Oakland Athletics -166; Over/Under: 8.5
(Get latest betting odds)

The Athletics and Chicago White Sox meet on Tuesday in MLB action at Rate Field. Here’s a White Sox vs Athletics Prediction. This article will include a White Sox vs Athletics Pick.

Athletics Betting Preview

The Athletics are 6-10 on the year and play the Brewers and Rangers next. The Athletics are batting .242 on the season, have a .309 OBP, and a .400 slugging percentage. The Athletics’ pitching staff has a 4.91 ERA and a 1.54 WHIP. Jacob Wilson leads the Athletics with 21 hits and 8 RBI, while Tyler Soderstrom and Lawrence Butler have combined for 34 hits and 14 RBI.

Jeffrey Springs gets the ball for the Athletics, and he is 2-1 with a 4.20 ERA and 16 strikeouts this season. Springs is 0-0 with a 0.00 ERA and three strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 4-11 on the year and play the Red Sox and Twins next. The Chicago White Sox are batting .201 on the season, have a .272 OBP, and a .300 slugging percentage. The Chicago White Sox pitching staff has a 3.55 ERA and a 1.28 WHIP. Brooks Baldwin leads the Chicago White Sox with 11 hits and 7 RBI, while Lenyn Sosa and Andrew Benintendi have combined for 19 hits and 11 RBI.

Sean Burke gets the ball for the Chicago White Sox, and he is 1-2 with a 6.08 ERA and 8 strikeouts this season. This will be Burke’s second career game against the Athletics.

Why the Chicago White Sox will win

  • The Athletics have lost 12 of their last 13 road games against AL Central opponents.
  • The White Sox have won five of their last six games as home underdogs against the Athletics.
  • The White Sox have covered the run line in each of their last eight games as home underdogs against AL West opponents.
  • The Athletics have failed to cover the run line in seven of their last eight games as favorites against American League opponents.
  • The Athletics have trailed after 3 innings in each of their last four night games against opponents that held a losing record.
  • The Athletics have trailed after 5 innings in each of their last four night games against opponents that held a losing record.
  • The Athletics have lost the first inning in three of their last four night games against opponents that held a losing record.

Why the Athletics will win

  • The Athletics have won each of their last five games against the White Sox following a home loss.
  • The White Sox have lost 24 of their last 27 home games following a home loss.
  • The Athletics have covered the run line in each of their last seven night games against AL Central opponents following a loss.
  • The White Sox have failed to cover the run line in four of their last five night games following a home loss.
  • The Athletics have led after 5 innings in each of their last four games against American League opponents.

Matchup/League Facts

  • The White Sox rank 30th in the league for hits this season (95).
  • The White Sox rank 30th in the league for slugging percentage this season (.300).
  • The Athletics rank 30th in the league for steals this season (3).
  • The Athletics rank 3rd in the league for strikeouts against this season (113).

White Sox vs Athletics Prediction

I’m not running to the window to back either the White Sox or the Athletics, as these are two bad teams not going anywhere fast. A pitching matchup of Burke and Springs doesn’t make things any better with what they’ve shown through a few starts. However, there are levels to suck, and it’s clear the Athletics are the better side. If the Athletics are going to hover around a .500 record and make things interesting over the next couple of months, they need to take advantage of games like this. Burke has allowed 13 hits and nine runs through 13.1 innings. Give me the Athletics and the RL for max betting value if forced to pick.

Randy Chambers's Free Pick: Oakland Athletics -1.5

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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