Astros vs Blue Jays Prediction 4/23/25 MLB Picks Today

The Toronto Blue Jays and Houston Astros meet Wednesday in MLB action at Daikin Park. Here’s an Astros vs Blue Jays Prediction. This article will include an Astros vs Blue Jays Pick.

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 12-12 on the year and play the Yankees, Red Sox, and Guardians next. The Toronto Blue Jays are batting .245 on the season, have a .318 OBP, and a .350 slugging percentage. The Toronto Blue Jays’ pitching staff has a 3.81 ERA and a 1.15 WHIP. Bo Bichette leads the Toronto Blue Jays with 31 hits and 13 RBI, while Vladimir Guerrero Jr. and George Springer have combined for 47 hits and 21 RBI.

Bowden Francis gets the ball for the Toronto Blue Jays, and he is 2-2 with a 3.13 ERA and 20 strikeouts this season. Francis is 0-1 with a 12.27 ERA and 9 strikeouts in his career against the Houston Astros.

Houston Astros Betting Preview

The Houston Astros are 12-11 on the year and play the Royals, Tigers, and White Sox next. The Houston Astros are batting .230 on the season, have a .307 OBP, and a .341 slugging percentage. The Houston Astros’ pitching staff has a 3.35 ERA and a 1.09 WHIP. Jose Altuve leads the Houston Astros with 28 hits and 9 RBI, while Jeremy Pena and Isaac Paredes have combined for 41 hits and 21 RBI.

Ryan Gusto gets the ball for the Houston Astros, and he is 2-1 with a 3.18 ERA and 17 strikeouts this season. This will be Gusto’s first career game against the Toronto Blue Jays.

Why the Houston Astros will win

• The Blue Jays have lost each of their last five games as road favorites against the Astros following a loss.
• The Astros have won five of their last six games as underdogs after playing the previous day.
• The Astros have covered the run line in each of their last 11 games as underdogs against AL East opponents.
• The Blue Jays have failed to cover the run line in 10 of their last 11 games as road favorites against AL West opponents following a loss.
• The Astros have led after 5 innings in each of their last six games against the Blue Jays at Daikin Park.
• The Astros have won the first inning in three of their last four games as underdogs against the Blue Jays at Daikin Park.
• The Blue Jays have trailed after 3 innings in four of their last five road games against AL West opponents that held a winning record.

Why the Toronto Blue Jays will win

• The Astros have lost each of their last eight Wednesday games.
• The Blue Jays have won each of their last five night games against American League opponents that held a winning record.
• The Blue Jays have covered the run line each of their last six road games against teams that held a winning record.
• The Astros have failed to cover the run line in each of their last eight Wednesday games.
• The Blue Jays have led after 5 innings in eight of their last nine night games against opponents that held a winning record.
• The Blue Jays have won the first inning in four of their last five night games against AL West opponents that held a winning record.
• The Blue Jays have led after 3 innings in six of their last seven games as favorites.

Houston Astros Player Prop Facts

• Isaac Paredes has hit a home run in four of the Astros’ last five games against AL opponents.
• Jeremy Pena has recorded a Double in three of his last four appearances with the Astros as home underdogs against AL East opponents.
• Isaac Paredes has recorded at least one RBI in each of the Astros’ last five games against AL opponents.
• Jeremy Pena has recorded at least one Single in each of the Astros’ last seven games against AL opponents.
• Yordan Alvarez has scored at least one run in each of his last nine appearances with the Astros as underdogs against AL East opponents.
• Jeremy Pena has recorded at least one hit in each of the Astros’ last 13 games.
• Jake Meyers ranks T7th in the league in Steals (7) this season.

Toronto Blue Jays Player Prop Facts

• George Springer has hit at least one home run in three of his last five appearances at Daikin Park against AL West opponents that held a winning record.
• George Springer has recorded a Double in three of the Blue Jays’ last four games against AL West opponents that held a winning record.
• George Springer has scored at least one run in seven of the Blue Jays’ last eight games against AL West opponents that held a winning record.
• Alejandro Kirk has recorded at least one hit in 16 of his last 17 appearances against opponents that held a winning record.
• Daulton Varsho has recorded at least one RBI in each of his last four appearances at Daikin Park against AL opponents that held a winning record.
• Myles Straw has recorded a Single in each of his last six road appearances against opponents that held a winning record.
• Bo Bichette ranks T6th in the league in Hits (31) this season.

Astros vs Blue Jays Prediction

The Blue Jays and Astros have been heading in different directions. The Blue Jays, all of a sudden, can’t string together offense, and the pitching hasn’t been much better. Francis has been respectable, allowing 16 hits and eight earned runs in 23 innings, but that won’t matter much if the offense doesn’t bounce back.

The Astros are playing their best ball of the season over the last week, and Gusto is off to a fine rookie season. Gusto has allowed 18 hits and six runs through 17 innings while averaging a strikeout per frame. Gusto is also going deeper into games as of late. I’ll ride the hot hand and side with the Astros for the sweep.