Twins vs White Sox Prediction 4/24/25 MLB Picks Today

In this article, we will formulate a Twins vs White Sox prediction for this MLB game on Thursday, April 24, at Target Field in Minneapolis, Minnesota. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Betting Preview

The Chicago White Sox (5-19, 1-11 Away) won their first series of the season by beating the Red Sox, but since then, they have been swept by the Athletics, lost three out of four against the Red Sox, and lost the opening two games of the current series against the Twins. The White Sox had a 3-2 lead last night in Minneapolis but ended with a 6-3 loss. Bryse Wilson pitched for 2.2 innings in a no-decision, allowing one run on five hits with two strikeouts and three walks. Jordan Leasure took the loss.

This season, the White Sox average 3.12 runs per game (29th in the MLB) on a .200/.275/.303 slash line. Regarding pitching, the White Sox’s staff has a 4.35 ERA (22nd) and 1.38 WHIP (24th). Andrew Vaughn leads the White Sox with a .149 batting average, three home runs, and ten RBI this season.

Shane Smith will take the mound for the White Sox on Thursday. The 25-year-old right-hander has a 0-1 record in four starts this year with a 2.82 ERA and 0.94 WHIP in 22.1 innings.

Minnesota Twins Betting Preview

The Minnesota Twins (9-15, 6-5 Home) beat the Mets at home, suffered a series sweep by the Braves on the road, and then returned home to defeat the White Sox in the first two games of the current series. After winning 4-2 in Game 1, the Twins secured a 6-3 victory in Game 2. Byron Buxton and Trevor Larnach led the offense with two RBI apiece, while David Festa pitched for 4.0 innings in a no-decision, allowing two runs on four hits with five strikeouts and three walks. Justin Topa was credited with the win.

This year, the Twins average 3.54 runs per game (25th in the MLB) on a .216/.294/.348 triple-slash. When it comes to pitching, the Twins’ staff has a 3.89 ERA (13th) and 1.24 WHIP (13th). Byron Buxton leads the Twins with a .230 batting average, five home runs, and 12 RBI this season.

The projected starting pitcher for the Twins is Chris Paddack, who is 0-2 in four starts this season, with a 7.27 ERA and 1.56 WHIP in 17.1 innings.

Why the White Sox will cover

• The Twins have lost eight of their last 11 games as home favorites following a win.
• The Twins have failed to cover the run line in each of their last five day games at Target Field following a win.
• The White Sox have covered the run line in four of their last five day games against American League opponents following a road loss.

Total Runs Facts

• Five of the Twins’ last six games as home favorites have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 12 of the Twins’ last 13 day games.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the White Sox’s last five day games at Target Field.

Matchup/League Facts

• The Twins rank 26th in the league for RBIs this season (80).
• The Twins rank 26th in the league for batting average this season (.216).
• The White Sox rank 30th in the league for slugging percentage this season (.303).
• The White Sox rank T29th in the league for doubles this season (27).

Twins vs White Sox Prediction

The Twins won eight of the previous ten H2H encounters. This season, the Twins lead the series 4-1; following Chicago’s 9-0 win, Minnesota won four straight. Chris Paddack is not pitching well this year and has allowed a .273 BA in 33 at-bats against the White Sox. Shane Smith is Chicago’s best starter this season, and he allowed a .133 BA in 15 at-bats against the Twins. Paddack did improve in his last two starts, but he already posted a 24.30 ERA in 3.1 innings against the White Sox this year, and I think the visitors can cause him problems again on Thursday. I am backing Chicago to stay close and cover the run line.