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Athletics vs Mariners Prediction 5/6/25 MLB Picks Today

Seattle Mariners (20-14) vs. Athletics (20-16)
May 6, 2025 10:05 pm EDT
The Line: Athletics -125 / Seattle Mariners 105; Over/Under: 9.5
(Get latest betting odds)

The Seattle Mariners and Athletics meet Tuesday in MLB action at Sutter Health Park. Here’s an Athletics vs Mariners Prediction. This article will include an Athletics vs Mariners Pick.

Seattle Mariners Betting Preview

The Seattle Mariners are 20-14 on the year and play the Blue Jays, Yankees, and Padres next. The Seattle Mariners are batting .245 on the season, have a .340 OBP, and a .415 slugging percentage. The Seattle Mariners’ pitching staff has a 3.75 ERA and a 1.30 WHIP. J.P. Crawford leads the Seattle Mariners with 32 hits and 17 RBI, while Cal Raleigh and Jorge Polanco have combined for 62 hits and 50 RBI.

Emerson Hancock gets the ball for the Seattle Mariners, and he is 1-1 with a 6.62 ERA and 15 strikeouts this season. This will be Hancock’s second career game against the Athletics.

Athletics Betting Preview

The Athletics are 20-16 on the year and play the Yankees, Dodgers, and Giants next. The Athletics are batting .257 on the season, have a .317 OBP, and a .423 slugging percentage. The Athletics’ pitching staff has a 4.42 ERA and a 1.41 WHIP. Jacob Wilson leads the Athletics with 46 hits and 20 RBI, while Tyler Soderstrom and Brent Rooker have combined for 73 hits and 43 RBI.

Jeffrey Springs gets the ball for the Athletics, and he is 4-3 with a 4.98 ERA and 28 strikeouts this season. Springs is 2-0 with a 2.19 ERA and 30 strikeouts in his career against the Seattle Mariners.

Why the Athletics will win

  • The Athletics have won eight of their last nine night games after playing the previous day.
  • The Mariners have lost 12 of their last 13 Tuesday games.
  • The Athletics have covered the run line in each of their last four games against the Mariners.
  • The Mariners have failed to cover the run line in four of their last five road games after going to extra innings.
  • The Athletics have led after 5 innings in four of their last five games against the Mariners.
  • The Mariners have lost the first inning in three of their last four night games against AL West opponents that held a winning record.
  • The Athletics have led after 3 innings in six of their last eight games as favorites against AL West opponents.

Why the Seattle Mariners will win

  • The Mariners have won each of their last 10 games as underdogs against the Athletics.
  • The Athletics have lost each of their last six home games following an extra innings win.
  • The Mariners have covered the run line in each of their last 10 games as underdogs against the Athletics.
  • The Athletics have failed to cover the run line in each of their last six games as favorites following a home win.
  • The Mariners have led after 3 innings in seven of their last eight games as road underdogs against AL West opponents.
  • The Athletics have trailed after 5 innings in seven of their last eight Tuesday night games as home favorites.

Athletics Player Prop Facts

  • Luis Urias has hit a home run in each of the Athletics’ last two games as home favorites.
  • Brent Rooker has recorded a Double in each of the Athletics’ last four home games against AL opponents.
  • Miguel Andujar has recorded an RBI in each of his five previous appearances with the Athletics as favorites against AL West opponents.
  • Miguel Andujar has scored a run in each of his last six appearances with his team as a home favorite against AL West opponents.
  • Miguel Andujar has recorded at least one Single in each of his last seven appearances with his team as a favorite against AL West opponents.
  • Lawrence Butler has recorded at least one hit in each of the Athletics’ last 20 home games against AL West opponents.
  • Jacob Wilson ranks 3rd in the league in Hits (46) this season.

Seattle Mariners Player Prop Facts

  • Cal Raleigh has hit a home run in three of the Mariners’ last four games against AL West opponents that held a winning record.
  • J.P. Crawford has recorded at least one Single in 12 of his last 13 appearances.
  • J.P. Crawford has recorded at least one hit in each of his last 13 appearances.
  • Jorge Polanco has scored at least one run in each of his last seven appearances in night games.
  • Jorge Polanco has recorded at least one RBI in each of the Mariners’ last five night games against AL West opponents that held a winning record.
  • Cal Raleigh ranks 1st in the league in Home Runs (12) this season.

Athletics vs Mariners Prediction

The Mariners still have issues finishing games here and there, and last night wasn’t great. It could be tough to rebound from such efforts. Hancock also hasn’t been great this season, allowing 26 hits and 13 runs in 17.2 innings. Yes, Hancock has been better lately, but he still has an ERA over five for his career in 19 starts. The Athletics continue to play surprising baseball, which includes wins in 10 of their last 13 games. Wins like last night only add to the confidence in the clubhouse.

Springs has been hittable all season, but he’s coming off six shutout innings against the Rangers. I’m not sure how long this run will last, but the Athletics have this feel-good mojo going, and I’m going to ride that as long as it lasts.

Randy Chambers's Free Pick: Athletics -125

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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