Reds vs White Sox Prediction 5/13/25 MLB Picks Today

In this article, we will formulate a Reds vs White Sox prediction for this MLB game on Tuesday, May 13th at Great American Ball Park in Cincinnati, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Cincinnati Reds Betting Preview

The Cincinnati Reds are 20-22 this year after they lost two out of three against the Astros by scores of 0-3, 13-9, and 0-6. In their game three loss, Cincinnati fell behind in the third inning and never got back into the game, as the offense really struggled to get on base. The Reds recorded just two hits, and they committed one error in the game, while they were led by Steer and Trevino, who both had one hit in the loss. Cincinnati started Petty, who allowed six hits and four earned runs over 3.0 innings for the loss, while Barlow allowed one hit and one earned run over 1.0 inning out of the bullpen. 

Prior to that series, the Reds lost three out of four against the Braves and two out of three against the Nationals. Cincinnati has lost seven of its last nine games, and they are currently fourth in the NL Central standings. The Cincinnati pitching staff has a 3.75 ERA with a 1.19 WHIP and a .222 opponent batting average, while their offense has scored 198 runs with a .237 batting average and a .321 on-base percentage this season. Elly De La Cruz has led Cincinnati with six home runs and 29 RBIs, while Austin Hays has added five home runs and 13 RBIs this year. The projected starting pitcher for Cincinnati is Andrew Abbott, who is 2-0 with a 2.25 ERA and a 1.17 WHIP over 24.0 innings pitched this year. 

Chicago White Sox Betting Preview

The Chicago White Sox are 12-29 this season after they won two out of three against the Marlins by scores of 6-2, 1-3, and 4-2. In their game three win, Chicago was tied at one in the fourth inning, but they scored three runs in the sixth to pull away with the win. The White Sox recorded seven hits and they committed one error in the game, while they were led by Elko, who went 1-3 with one home run and three RBIs in the win. Chicago started Burke, who allowed four hits and one earned run over 4.0 innings, while Vasil pitched three innings out of the bullpen and got the win. 

Prior to that series, the White Sox lost all four against the Royals, but did win two out of three against the Astros before that. Chicago has lost five of their last seven games, and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.10 ERA with a 1.39 WHIP and a .247 opponent batting average, while the offense has scored 139 runs with a .214 batting average and a .291 on-base percentage this season. Luis Robert has led Chicago with five home runs and 16 RBIs, while Andrew Vaughn has added five home runs and 17 RBIs this year. The projected starting pitcher for Chicago is Jonathan Cannon, who is 2-4 with a 4.09 ERA and a 1.45 WHIP over 44.0 innings pitched this season. 

Why the Reds will beat the White Sox

• The White Sox have lost each of their last 11 night games against NL Central opponents.
• The home team has won seven of the White Sox’s last eight games.
• The White Sox have failed to cover the run line in each of their last four games as road underdogs against National League opponents following a home win.
• The Reds have covered the run line in 10 of their last 12 games following a road loss.
• The Reds have led after 3 innings in each of their last three games against the White Sox.
• The Reds have led after 5 innings in five of their last six games against the White Sox.

Total Runs Facts

• Four of the White Sox’s last five road games against NL Central opponents have gone OVER the total runs line.
• Six of the Reds’ last eight games have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Reds’ last six night games at Great American Ball Park.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the White Sox’s last eight games as underdogs against NL Central opponents.

Cincinnati Reds Player Prop Facts

• Will Benson has hit a home run in each of his last two appearances in night games against AL teams that held a losing record.
• TJ Friedl has recorded at least one RBI in each of his last five appearances against AL Central opponents that held a losing record.
• TJ Friedl has recorded at least one Single in each of the Reds’ last six games against AL Central opponents.
• Tyler Stephenson has recorded at least one hit in each of his last nine home appearances against AL opponents.
• Elly De La Cruz has scored at least one run in eight of the Reds’ last nine games against AL opponents that held a losing record.
• Jose Trevino has recorded a Double in five of his last six appearances against AL opponents.

Chicago White Sox Player Prop Facts

• Luis Robert has recorded at least one Single in nine of his last 10 road appearances against NL Central opponents.
• Andrew Vaughn has recorded at least one hit in each of the White Sox’s last 10 night games against NL Central opponents that held a losing record.
• Luis Robert has scored at least one run in each of his last six appearances against the Reds.
• Andrew Benintendi has hit at least one home run in three of the White Sox’s last four games against NL Central opponents that held a losing record.
• Andrew Vaughn has recorded an RBI in four of the White Sox’s last five games against NL opponents.

David Racey is 25-7 (78%) in the MLB over the last seven days. Click here for his premium plays for today!

Reds vs White Sox Prediction 

Chicago comes into this matchup after getting a series win over Miami, but they are just 3-17 on the road this year. The White Sox have really struggled at the plate, and they have scored one run or fewer in three of their last five games. Cincinnati has lost three of their last four, and they have been shut out in two of their last three. The Reds are starting Abbott, who has allowed one earned run or fewer in four of his last five starts. The White Sox are going with Cannon, who has allowed two earned runs or fewer in three of his last five outings. Both pitchers have been very good recently, but I don’t trust Chicago at the plate. Take the Reds -1.5 here.