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Rays vs Astros Prediction 5/19/25 MLB Picks Today

Houston Astros (24-22) vs. Tampa Bay Rays (21-25)
May 19, 2025 7:05 pm EDT
The Line: Tampa Bay Rays -135 / Houston Astros 114; Over/Under: 9
(Get latest betting odds)

The Houston Astros and Tampa Bay Rays meet Monday in MLB action at George M. Steinbrenner Field. Here’s a Rays vs Astros Prediction. This article will include a Rays vs Astros Pick.

Houston Astros Betting Preview

The Houston Astros are 24-22 on the year and play the Mariners, Athletics, and Rays next. The Houston Astros are batting .245 on the season, have a .317 OBP, and a .372 slugging percentage. The Houston Astros’ pitching staff has a 3.39 ERA and a 1.12 WHIP. Jeremy Pena leads the Houston Astros with 52 hits and 23 RBI, while Isaac Paredes and Jose Altuve have combined for 85 hits and 38 RBI.

Colton Gordon gets the ball for the Houston Astros, and he is 0-0 with a 6.23 ERA and 3 strikeouts this season. This will be Gordon’s first career game against the Tampa Bay Rays.

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 21-25 on the year and play the Blue Jays, Twins, and Astros next. The Tampa Bay Rays are batting .242 on the season, have a .306 OBP, and a .363 slugging percentage. The Tampa Bay Rays pitching staff has a 3.91 ERA and a 1.22 WHIP. Jonathan Aranda leads the Tampa Bay Rays with 43 hits and 21 RBI, while Yandy Diaz and Junior Caminero have combined for 81 hits and 44 RBI.

Ryan Pepiot gets the ball for the Tampa Bay Rays, and he is 2-5 with a 3.93 ERA and 45 strikeouts this season. This will be Pepiot’s first career game against the Houston Astros.

Why the Tampa Bay Rays will win

  • The Astros have lost each of their last nine road games following a win.
  • The Rays have won each of their last four games following a road loss.
  • The Astros have failed to cover the run line in eight of their last nine road games against teams that held a losing record.
  • The Rays have covered the run line in each of their last five games against the Astros following a loss.
  • The Astros have trailed after 3 innings in four of their last five road games against opponents that held a losing record.
  • The Astros have lost the first inning in three of their last four road games against American League opponents that held a losing record.
  • The Rays have led after 5 innings in each of their last four games against American League opponents.

Why the Houston Astros will win

  • The Rays have lost six of their last seven games as favorites against American League opponents.
  • The Astros have won four of their last five games as road underdogs against the Rays.
  • The Rays have failed to cover the run line in each of their last 12 games as home favorites against AL West opponents.
  • The Astros have covered the run line in each of their last 11 games as underdogs against AL East opponents.
  • The Rays have trailed after 3 innings in five of their last six home games against American League opponents.
  • The Rays have lost the first inning in four of their last five home games against American League opponents.
  • The Rays have trailed after 5 innings in each of their last six home games against American League opponents.

Tampa Bay Rays Player Prop Facts

  • Yandy Diaz has hit a home run in three of the Rays’ last four home games against opponents that held a winning record.
  • Yandy Diaz has recorded at least one RBI in each of the Rays’ last three games.
  • Josh Lowe has recorded a Single in seven of his last eight appearances in night games.
  • Josh Lowe has recorded at least one hit in each of his last 12 Monday appearances.
  • Ha-Seong Kim has scored a run in each of his last three appearances against opponents that held a winning record.
  • Jose Caballero ranks T7th in the league in Steals (12) this season.

Houston Astros Player Prop Facts

  • Jeremy Pena has hit a home run in four of his last five road appearances against AL East opponents.
  • Isaac Paredes has recorded a Double in each of the Astros’ last three games against opponents that held a losing record.
  • Jeremy Pena has recorded at least one Single in each of the Astros’ last eight games against opponents that held a losing record.
  • Jose Altuve has recorded at least one hit in each of his last 10 appearances with the Astros as underdogs against the Rays.
  • Yordan Alvarez has scored at least one run in each of his last nine appearances with the Astros as underdogs against AL East opponents.
  • Yordan Alvarez has recorded at least one RBI in each of his last five appearances with the Astros as road underdogs against AL East opponents.

Rays vs Astros Prediction

The Astros are showing signs of life lately, but they’re throwing Gordon on the mound, a guy who has just 4.1 MLB innings under his belt and will pitch on the road for the first time. The Rays are due for a bounce-back effort after a disappointing effort against the Marlins. Pepiot has a 3.93 ERA and 1.29 WHIP on the season, and he’s allowed just six runs in his last 16.1 innings. Pepiot has allowed three or fewer runs in eight of his last nine starts. The Rays are at home with the more trustworthy pitcher. Give me the home team to draw first blood.

Randy Chambers's Free Pick: Tampa Bay Rays -135

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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