Twins vs Royals Prediction 5/23/25 MLB Picks Today

The Kansas City Royals and the Minnesota Twins meet Friday in MLB action from Target Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Twins vs Royals Prediction.

Starting Pitching Matchup

The Kansas City Royals will send out Noah Cameron for the start here, and Cameron is 1-1 with a 0.71 ERA and 6 strikeouts this season. This will be Cameron’s first career start against the Twins. The Minnesota Twins will trot out Pablo Lopez for the start here, and Lopez is 4-2 with a 2.40 ERA and 49 strikeouts this season. In his last five starts against the Royals, Lopez is 4-0 with a 2.48 ERA and 37 strikeouts.

Kansas City Royals Recap

The Kansas City Royals come into this game looking to build on their 8-4 win over the San Francisco Giants last time out to improve to 28-23 on the year. After this series, the Royals will head home for a series against the Reds.

Royals Finally Pick Up Series Win

Bobby Witt Jr. has a team-high 60 hits with 19 doubles and 16 stolen bases, along with 3 triples, 5 home runs, and 28 RBIs, while Vinnie Pasquantino has 45 hits with 5 doubles, a triple, 8 home runs, and 29 RBIs. Maikel Garcia added 56 hits with 13 doubles, 5 home runs, and 22 RBIs, and 10 stolen bases, and Salvador Perez also has 3 home runs and 23 RBIs, but also has the unfortunate distinction of leading the Royals with 45 strikeouts so far this season.

Why the Kansas City Royals will win

• The underdogs have won five of the Royals’ last six games.
• The Twins have lost four of their last five games as favorites against AL Central opponents.
• The underdogs have covered the run line in each of the Royals’ last 12 games.
• The Twins have failed to cover the run line in eight of their last nine home games against American League opponents that held a winning record.

Kansas City Royals Player Prop Facts

• Bobby Witt Jr. has hit a home run in two of the Royals’ last three road games against the Twins.
• Bobby Witt Jr. has recorded a Double in four of the Royals’ last five games against the Twins.
• Bobby Witt Jr. has recorded at least one RBI in each of the Royals’ last five games against AL Central opponents.
• Michael Massey has recorded at least one Single in each of the Royals’ last six night games against AL Central opponents that held a winning record.
• Bobby Witt Jr. has scored at least one run in each of the Royals’ last six Friday games against AL Central opponents that held a winning record.
• Bobby Witt Jr. has recorded at least one hit in each of the Royals’ last 19 games as road underdogs against AL Central opponents.
• Bobby Witt Jr. ranks T3rd in the league in Steals (16) this season.

Minnesota Twins Recap

The Minnesota Twins come into this game looking to bounce back from a 5-1 loss at the hands of the Guardians in their last matchup to fall to 27-22 on the year. After this series, the Twins will head on the road for a series against the Tampa Bay Rays.

Twins Win 8 Of Their Last 10 Despite Loss

Byron Buxton has 41 hits along with 5 doubles, a team-high 10 home runs, and 27 RBIs with 8 stolen bases and 3 triples, while Carlos Correa has 35 hits with 8 doubles, and Willi Castro has 23 hits with 7 doubles as well. Harrison Bader added 4 home runs and 18 RBIs while Buxton contributed a team-high 56 strikeouts as well this season. Ty France has also added 43 hits, 8 doubles, 3 home runs, and 24 RBIs, and Trevor Larnach chipped in 44 hits with 7 home runs and 23 RBIs as well this season.

Why the Minnesota Twins will win

• The Twins have won each of their last 10 home games against the Royals following a loss.
• The Royals have lost 22 of their last 23 games at Target Field following a win.
• The Twins have covered the run line in each of their last six night games against the Royals at Target Field following a loss.
• The Royals have failed to cover the run line in each of their last six night games against the Twins at Target Field following a win.

Minnesota Twins Player Prop Facts

• Ty France has hit a home run in each of the Twins’ last two games against the Royals.
• Ty France has recorded at least one RBI in six of his last seven home appearances against AL opponents that held a winning record.
• Pablo Lopez has recorded a win in each of his five previous appearances with the Twins as favorites against the Royals.
• Pablo Lopez has recorded six or more strikeouts in each of his last six appearances.
• Ty France has recorded at least one Single in each of his last six appearances against AL Central opponents that held a winning record.
• Harrison Bader has recorded at least one hit in each of his last 13 appearances against opponents that held a winning record.
• Byron Buxton has scored at least one run in each of his last seven appearances against AL opponents.

Total Runs Facts

• Each of the last eight games between the Royals and Twins have gone UNDER the total runs line.
• Fourteen of the Royals’ last 15 night games as underdogs have gone UNDER the total runs line.

Twins vs Royals Prediction

I’m on the Twins in this one. I get the case to be made for the Royals, as I’ve been a big backer of Kansas City for much of the year. However, there’s really no disputing the difference between this Royals team from their play at home to their numbers on the road, and it is a night-and-day difference when you do some digging. The Twins have still been a really consistent team with some really solid pitching numbers as of late, and I think they get the series-opening win here. Give me the Twins.