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Astros vs Angels Prediction 6/20/25 MLB Picks Today

Astros vs Angels
June 20, 2025 9:38 pm EDT
The Line: Astros -185 / Angels +155 / Over/Under: 8
(Get latest betting odds)

The Houston Astros are visiting the Los Angeles Angels on Friday, June 20th at the Angel Stadium in the opening game of this series. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Astros vs Angels Prediction. We will examine:

The Los Angeles Angels’ recent form and player performance

The Houston Astros’ recent form and player performance

Recent betting trends and streaks involving the Los Angeles Angels

Recent betting trends and streaks involving the Houston Astros

Recent betting trends in games played between the Houston Astros vs Los Angeles Angels

A summary that ties it all together and produces a favorable betting outcome for the Houston Astros vs Los Angeles Angels game

Los Angeles Angels Preview

The Los Angeles Angels have a 36-38 record this season and are sitting in 4th place in the AL West. The Angels have a 15-16 home record and 38-35 in over/under. They are coming off a 3-7 home defeat by the Yankees, which ended their previous three-game winning streak. Under is 4-0 in their last 4 games, and they are playing the Red Sox and the Nationals next.

The Angels have a .225 batting average this season, a .287 OBP, and a .398 Slugging percentage. LA’s pitching staff has a 4.67 ERA and 1.47 WHIP. Nolan Schanuel leads the Angels with 72 hits, and he is the team’s best hitter with a .278 batting average. Taylor Ward leads the team with 50 RBI and a team-high 19 home runs.

Yusei Kikuchi (L) will take the mound for the Angels, and he has a 2-6 record, 3.05 ERA, and 1.48 WHIP. He has been excellent at home with a 1.05 ERA across six home starts, but he has given up 3 runs in two of his last three starts. Yusei Kikuchi has a record of 1-5 with an ERA of 6.00 and 55 strikeouts in 14 appearances against the Astros in his career.

Houston Astros Preview

The Houston Astros have a 43-32 record this season and are sitting in first place in the AL West. The Astros have a 16-19 road record and 31-41 in over/under. They are coming off a 4-6 road defeat by the Athletics, but are 7-2 in their last 9 games. Over is 3-0 in their last 3 games, and they are playing the Cubs and the Phillies next.

The Astros have a .258 batting average this season, a .324 OBP, and a .402 slugging percentage. Houston’s pitching staff has a 3.42 ERA and 1.15 WHIP. Jeremy Pena leads the Astros with 94 hits, and he is the team’s best hitter, with a .322 batting average. Isaac Paredes leads the team in RBI with 44, adding a team-high 15 home runs.

Hunter Brown (R) is the projected starter for the Astros, and he has an 8-3 record, 1.88 ERA, and 0.93 WHIP. He has been weaker on the road, with a 2.42 ERA across 8 road starts, and he has given up 2 runs or less in his last four starts. Hunter Brown has a record of 1-1 with an ERA of 3.31 and 13 strikeouts in 3 appearances versus the Angels in his career.

Why the Los Angeles Angels will win

  • The Angels have won each of their last eight night games after playing the previous day.
  • The Astros have lost each of their last eight games after going to extra innings.
  • The Angels have covered the run line each of their last eight night games against teams that held a winning record.
  • The Astros have failed to cover the run line in seven of their last eight games after going to extra innings.
  • The Angels have led after 5 innings in six of their last seven night games against AL West opponents.

Why the Houston Astros will win

  • The Astros have won each of their last 10 games against the Angels following a loss.
  • The Angels have lost each of their last six night games against the Astros at Angel Stadium of Anaheim following a road loss.
  • The Astros have covered the run line each of their last 11 Friday games against AL West opponents that held a losing record.
  • The Angels have failed to cover the run line in nine of their last 10 games as home underdogs against American League opponents following a road loss.
  • The Astros have led after 3 innings in five of their last six games against the Angels.
  • The Astros have led after 5 innings in five of their last six games against the Angels.
  • The Angels have lost the first inning in three of their last four home games against opponents that held a winning record.

Total Runs Facts

  • Each of the Astros’ last five road games following an extra innings loss have gone UNDER the total runs line.
  • Each of the Angels’ last five night games against American League opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Astros’ last seven Friday games against AL West opponents.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Angels’ last six night games.

Matchup/League Facts

  • The Angels rank 30th in the league for on-base percentage this season (.287).
  • The Angels rank 29th in the league for doubles this season (96).
  • The Astros rank 1st in the league for strikeouts this season (734).
  • The Astros rank 2nd in the league for batting average this season (.258).

Astros vs Angels Prediction

The Astros are 8-2 in their last 10 overall meetings against the Angels, and have won their last three visits in Los Angeles. Over is 5-1 in their last 6 meetings.

In this Astros vs Angels Prediction, the Astros are coming as -185 road favorites. Houston is rightfully favored, as they have a better overall record, but they have been below average on the road, and the Angels have been below average at home as well. The bullpen differential is huge, as the Astros have the 5th-best bullpen ERA this season, while the Angels are fourth to last.  The Astros are also the 4th-best team against lefties, while the Angels are second-to-last against righties. Kikuchi has been terrible against Astros bats in his career, and he is due to some negative regression, having a 4.66 expected ERA. Take the Houston Astros to win this one on the road.

Nikos Lagouretos's Free Pick: Houston Astros -185

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