Yankees vs Orioles Prediction 6/21/25 MLB Picks Today

In this article, we will formulate a Yankees vs Orioles prediction for this MLB game on Saturday, June 21st at Yankee Stadium in New York. Let’s take a look at the prediction for this MLB matchup. 

New York Yankees Betting Preview

The New York Yankees are 43-32 this year after they lost game one by a score of 5-3 on Friday night. New York led 3-2 in the third inning, but they went scoreless over their last six innings for the loss. The Yankees recorded 10 hits in the game, and they were led by Judge, Chisholm Jr., and Dominguez, who all had one RBI in the loss. New York started Fried, who allowed seven hits and three earned runs over 6.0 innings, while Weaver picked up the loss in relief. 

Prior to this series, the Yankees lost three out of four against the Angels and all three against the Red Sox. New York has lost seven of their last eight games, and they are currently first in the AL East standings. The New York pitching staff has a 3.54 ERA with a 1.19 WHIP and a .220 opponent batting average, while the offense has scored 382 runs with a .254 batting average and a .336 on-base percentage this season. Aaron Judge has led New York with 27 home runs and 61 RBIs, while Trent Grisham has added 14 home runs and 30 RBIs this year. The projected starting pitcher for New York is Clarke Schmidt, who is 3-3 with a 3.16 ERA and a 1.15 WHIP over 62.2 innings pitched this year. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 33-42 this season after they won game one on Friday night. Baltimore led 2-0 in the first inning, but they needed the tying run in the sixth and the go-ahead run in the eighth for the win. The Orioles recorded 11 hits in the game, and they were led by Sanchez, who went 2-3 with two RBIs in the win. Baltimore started Sugano, who allowed seven hits and three earned runs over 3.2 innings, while Blewett picked up the win and Bautista got the save. 

Prior to this series, the Orioles split four games with the Rays and won all three against the Angels. Baltimore has won six of their last eight games, and they are currently last in the AL East standings. The Baltimore pitching staff has a 4.90 ERA with a 1.43 WHIP and a .270 opponent batting average, while their offense has scored 302 runs with a .241 batting average and a .306 on-base percentage this season. Cedric Mullins has led Baltimore with 12 home runs and 35 RBIs, while Ryan O’Hearn has added 10 home runs and 28 RBIs this year. The projected starting pitcher for Baltimore is Zach Eflin, who is 6-3 with a 4.81 ERA and a 1.24 WHIP over 58.0 innings pitched this season. 

Why the Yankees will beat the Orioles

• The Yankees have won seven of their last eight day games against American League opponents following a home loss.
• The Orioles have lost seven of their last eight day games against American League opponents that held a winning record.
• The Yankees have covered the run line in five of their last six day games following a home loss.
• The Orioles have failed to cover the run line in five of their last six day games against American League opponents that held a winning record.
• The Orioles have trailed after 5 innings in each of their last six Saturday day games against opponents that held a winning record.
• The Orioles have trailed after 3 innings in each of their last seven Saturday day games against opponents that held a winning record.
• The Yankees have won the first inning in three of their last four day games against AL East opponents that held a losing record.

Total Runs Facts

• Each of the Yankees’ last nine games have gone UNDER the total runs line.
• Six of the Orioles’ last seven games against AL East opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Yankees’ last six day games.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Orioles’ last four day games at Yankee Stadium.

New York Yankees Player Prop Facts

• Aaron Judge has hit a home run in each of the Yankees’ last five home games against the Orioles.
• Aaron Judge has recorded at least one RBI in each of the Yankees’ last seven games against the Orioles.
• Aaron Judge has recorded at least one hit in each of the Yankees’ last eight day games against AL opponents that held a losing record.
• Aaron Judge has scored at least one run in each of his last seven home appearances against the Orioles.
• Aaron Judge has recorded a Double in three of the Yankees’ last four day games against opponents that held a losing record.

Baltimore Orioles Player Prop Facts

• Zach Eflin has recorded a win in three of his last four appearances.
• Colton Cowser has hit a home run in three of the Orioles’ last four games against AL East opponents.
• Ryan Mountcastle has recorded an RBI in four of his last five appearances with the Orioles as underdogs against AL opponents.
• Gunnar Henderson has recorded at least one hit in each of the Orioles’ last 13 games against AL opponents.
• Tyler O’Neill has scored at least one run in each of his last eight Saturday appearances with his team as an underdog.
• Zach Eflin has recorded five or more strikeouts in eight of his nine previous appearances against the Yankees.
• Ryan Mountcastle has recorded at least one Double in three of his last four appearances against opponents that held a winning record.

Yankees vs Orioles Prediction 

Baltimore was able to stay hot with a win to open this series on Friday night, but they have a long way to go if they want to get back into the playoff race. The Orioles are 17-23 on the road this year, while the Yankees are 22-16 at home. New York is trending in the opposite direction, and they are in danger of dropping out of first in the AL East. The Yankees are starting Schmidt, who has allowed zero earned runs in three of his last four starts. The Orioles are going with Eflin, who has allowed 3+ earned runs in three of his last five. Take New York -1.5 here behind another strong start from Schmidt.