
Guardians vs Astros Prediction 7/8/25 MLB Picks Today
Guardians vs Astros
July 8, 2025 8:10 pm EDT
The Line: Guardians +185 / Astros -225 / Over/Under: 7
(Get latest betting odds)
The Cleveland Guardians are visiting the Houston Astros on Tuesday, July 8th at the Daikin Park in the second game of this series, with the Guardians having a 1-0 lead. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Guardians vs Astros Prediction. We will examine:
The Houston Astros’ recent form and player performance
The Cleveland Guardians’ recent form and player performance
Recent betting trends and streaks involving the Houston Astros
Recent betting trends and streaks involving the Cleveland Guardians
Recent betting trends in games played between the Cleveland Guardians vs Houston Astros
A summary that ties it all together and produces a favorable betting outcome for the Cleveland Guardians vs Houston Astros game
Houston Astros Preview
The Houston Astros have a 55-36 record this season and are sitting in first place in the AL West. The Astros have a 32-15 home record and 39-49 in over/under. They are coming off a 5-7 home defeat by the Guardians, which snapped their previous three-game winning streak. Over is 4-1 in their last 5 games, and they are playing the Rangers and the Mariners next.
The Astros have a .260 batting average this season, a .325 OBP, and a .413 slugging percentage. Houston’s pitching staff has a 3.52 ERA and 1.16 WHIP. Jeremy Pena leads the Astros with 102 hits, and he is the team’s best hitter, with a .322 batting average. Isaac Paredes leads the team in RBI with 49, adding a team-high 19 home runs.
Hunter Brown (R) is the projected starter for the Astros, and he has a 9-3 record, 1.82 ERA, and 0.90 WHIP.
Cleveland Guardians Preview
The Cleveland Guardians have a 41-48 record this season and are sitting in 4th place in the AL Central. The Guardians have a 21-25 road record and are 39-47 in over/under. They are coming off a 7-5 road victory over the Astros, which ended their previous 9-game losing streak. Under is 5-3 in their last 8 games, and are playing the White Sox and the Athletics next.
The Guardians have a .224 batting average this season, a .295 OBP, and a .363 Slugging percentage. Cleveland’s pitching staff has a 3.97 ERA and 1.36 WHIP. Steven Kwan leads the Guardians with 100 hits, while Jose Ramirez is the team’s best hitter with a .298 batting average, while leading the team both in RBI, with 42, and in home runs with 15.
Joey Cantillo (L) is the projected starting pitcher for the Guardians, and he has a 1-0 record, 3.41 ERA, and 1.39 WHIP.
Why the Houston Astros will win
- The Astros have won each of their last nine home games following a home loss.
- The Guardians have lost 10 of their last 11 games.
- The Guardians have failed to cover the run line in each of their last seven night games against the Astros following a win.
- The Astros have covered the run line in each of their last six night games against the Guardians following a loss.
- The Astros have led after 3 innings in six of their last eight home night games.
- The Astros have led after 5 innings in each of their last seven Tuesday games against the Guardians.
Why the Cleveland Guardians will win
- The underdogs have won each of the Astros’ last five games.
- The Astros have lost three of their last four night games against American League opponents.
- The Astros have failed to cover the run line in eight of their last nine games as home favorites against AL Central opponents.
- The Guardians have covered the run line in seven of their last eight road games after playing the previous day.
Total Runs Facts
- Six of the Astros’ last seven games against American League opponents have gone OVER the total runs line.
- Nine of the Guardians’ last 11 road games have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Guardians’ last six road games.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the Astros’ last 11 games as favorites against AL Central opponents.
Matchup/League Facts
- The Astros rank 1st in the league for batting average this season (.260).
- The Astros rank 1st in the league for strikeouts this season (876).
- The Guardians rank 30th in the league for hits this season (651).
- The Guardians rank 29th in the league for batting average this season (.224).
Guardians vs Astros Prediction
The Astros are 7-3 in their last 10 overall meetings against the Guardians, but both teams are tied 2-2 wins this season. The Astros are 3-2 in their last 5 home meetings against the Guardians, and under is 4-2 in their last 6 meetings.
In this Guardians vs Astros Prediction, the Astros are coming as -215 home favorites. The Astros are rightfully favored, as they have a far better overall record and have been one of the strongest home teams in the league, while the Guardians are below average on the road. Brown has been unhittable at home for the Astros with a 1.01 home ERA, and the Astros have both a better bullpen and a better offense. Take the Astros to cover the runline in this one.