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Pirates vs White Sox Prediction 7-20-25 MLB Picks

Chicago White Sox (34-65) vs. Pittsburgh Pirates (39-60)
July 20, 2025 5:35 pm EDT
The Line: Pittsburgh Pirates -145 / Chicago White Sox 119; Over/Under: 9
(Get latest betting odds)

The Chicago White Sox and Pittsburgh Pirates meet Sunday in MLB action at PNC Park. Here’s a Pirates vs White Sox Prediction. This article will include a Pirates vs White Sox Pick.

Chicago White Sox Betting Preview

The Chicago White Sox are 34-65 on the year and play the Rays, Cubs, and Phillies next. The Chicago White Sox are batting .222 on the season, have a .297 OBP, and a .349 slugging percentage. The Chicago White Sox pitching staff has a 4.10 ERA and a 1.38 WHIP. Lenyn Sosa leads the Chicago White Sox with 81 hits and 34 RBI, while Miguel Vargas and Chase Meidroth have combined for 140 hits and 47 RBI.

Aaron Civale gets the ball for the Chicago White Sox, and he is 1-6 with a 5.30 ERA and 36 strikeouts this season. Civale is 2-2 with a 3.40 ERA and 30 strikeouts in his career against the Pittsburgh Pirates.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 39-60 on the year and play the Tigers, Diamondbacks, and Giants next. The Pittsburgh Pirates are batting .230 on the season, have a .300 OBP, and a .340 slugging percentage. The Pittsburgh Pirates pitching staff has a 3.86 ERA and a 1.22 WHIP. Byran Reynolds leads the Pittsburgh Pirates with 84 hits and 46 RBI while Ke’Bryan Hayes and Andrew McCutchen have combined for 158 hits and 64 RBI.

Andrew Heaney gets the ball for the Pittsburgh Pirates, and he is 4-8 with a 4.59 ERA and 73 strikeouts this season. Heaney is 5-1 with a 4.31 ERA and 62 strikeouts in his career against the Chicago White Sox.

Why the Pittsburgh Pirates will win

  • The White Sox have lost each of their last 10 day games against teams that held a losing record.
  • The Pirates have won six of their last seven home games after playing the previous day.
  • The White Sox have failed to cover the run line in seven of their last eight day games against National League opponents that held a losing record.
  • The Pirates have covered the run line in eight of their last 10 day games against teams that held a losing record.
  • The Pirates have led after 5 innings in each of their last four day games against the White Sox.
  • The White Sox have trailed after 3 innings in each of their last six day games against NL Central opponents.

Why the Chicago White Sox will win

  • The Pirates have lost seven of their last eight games as home favorites against AL Central opponents.
  • The White Sox have won each of their last three games as road underdogs.
  • The Pirates have failed to cover the run line in each of their last nine home games against AL Central opponents.
  • The road team has covered the run line in each of the last seven games between the White Sox and Pirates.
  • The Pirates have trailed after 3 innings in five of their last six home games against American League opponents that held a losing record.
  • The Pirates have trailed after 5 innings in four of their last five home games against AL Central opponents.

Pittsburgh Pirates Player Prop Facts

  • Tommy Pham has hit a home run in three of his last 10 appearances after playing the previous day.
  • Andrew Heaney has recorded four or more strikeouts in each of his last 10 home appearances against AL opponents.
  • Bryan Reynolds has recorded at least one hit in each of the Pirates’ last 15 home games against AL Central opponents.
  • Andrew Heaney has recorded a win in each of his last three appearances with his team as a home favorite.
  • Andrew McCutchen has recorded a Double in four of his last five appearances against the White Sox after playing the previous day.
  • Oneil Cruz ranks 2nd in the league in Steals (30) this season.

Chicago White Sox Player Prop Facts

  • Luis Robert has hit a home run in two of his last three appearances with the White Sox against NL opponents.
  • Aaron Civale has recorded four or more strikeouts in each of his last seven appearances with his team as an underdog against NL opponents.
  • Michael A. Taylor has recorded a Double in each of his last three appearances with the White Sox as underdogs against NL opponents.
  • Mike Tauchman has recorded at least one hit in each of his last 11 road appearances against opponents that held a losing record.
  • Aaron Civale has recorded a win in three of his last four appearances against NL Central opponents that held a losing record.
  • Luis Robert ranks T9th in the league in Steals (24) this season.

Pirates vs White Sox Prediction

Give the White Sox credit for winning a couple of games, but they’re still a million games under a .500 record. Civale also has a 5.30 ERA and 1.48 WHIP, and he’s 0-6 as a starter for the Sox since coming over from the Brewers. Civale hasn’t won a game since June 2. Heaney isn’t off to the best start in July, but he has a 2.53 ERA and .219 allowed batting average in 46.1 home innings. As I’ve said unless times over the years, I’m not in the business of backing the White Sox. I’m just not. Give me the Pirates on Sunday afternoon.

Randy Chambers's Free Pick: Pittsburgh Pirates -145

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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