
Twins vs Nationals Prediction 7-25-25 MLB Picks
Washington Nationals (41-61) vs. Minnesota Twins (49-53)
July 25, 2025 9:10 pm EDT
The Line: Minnesota Twins -144 / Washington Nationals 118; Over/Under: 8.5
(Get latest betting odds)
The Washington Nationals and Minnesota Twins meet Friday in MLB action at Target Field. Here’s a Twins vs Nationals Prediction. This article will include a Twins vs Nationals Pick.
Washington Nationals Betting Preview
The Washington Nationals are 41-61 on the year and play the Astros, Brewers, and Athletics next. The Washington Nationals are batting .245 on the season, have a .311 OBP, and a .389 slugging percentage. The Washington Nationals pitching staff has a 5.20 ERA and a 1.41 WHIP. James Wood leads the Washington Nationals with 103 hits and 70 RBI, while CJ Abrams and Nathaniel Lowe have combined for 184 hits and 99 RBI.
MacKenzie Gore gets the ball for the Washington Nationals, and he is 4-9 with a 3.59 ERA and 140 strikeouts this season. This will be Gore’s first career game against the Minnesota Twins.
Minnesota Twins Betting Preview
The Minnesota Twins are 49-53 on the year and play the Red Sox, Guardians, and Tigers next. The Minnesota Twins are batting .241 on the season, have a .312 OBP, and a .401 slugging percentage. The Minnesota Twins pitching staff has a 4.17 ERA and a 1.26 WHIP. Byron Buxton leads the Minnesota Twins with 92 hits and 58 RBI while Carlos Correa and Ty France have combined for 169 hits and 74 RBI.
Zebby Matthews gets the ball for the Minnesota Twins, and he is 1-2 with a 6.26 ERA and 31 strikeouts this season. This will be Matthews’ first career game against the Washington Nationals.
Why the Minnesota Twins will win
- The Nationals have lost 11 of their last 12 games against teams that held a losing record.
- The Twins have won each of their last four games at Target Field following a loss.
- The Nationals have failed to cover the run line each of their last 12 games against teams that held a losing record.
- The Twins have covered the run line in three of their last four games.
- The Nationals have trailed after 3 innings in nine of their last 10 games as underdogs against American League opponents.
- The Nationals have trailed after 5 innings in seven of their last eight night games against AL Central opponents that held a losing record.
Why the Washington Nationals will win
- The Nationals have won four of their last five games as road underdogs against American League opponents following a loss.
- The Twins have lost five of their last six games as home favorites against National League opponents following a road loss.
- The Twins have failed to cover the run line in each of their last six games as favorites against NL East opponents.
- The Nationals have covered the run line in each of their last six games against the Twins following a loss.
- The Nationals have led after 5 innings in each of their last three night games.
- The Twins have trailed after 3 innings in five of their last six games as home favorites against NL East opponents.
Minnesota Twins Player Prop Facts
- Byron Buxton has hit a home run in each of his last two appearances after not playing the previous day.
- Byron Buxton has recorded at least one hit in each of his last 11 home appearances against NL opponents that held a losing record.
- Carlos Correa has recorded a Double in three of the Twins’ last four home games against NL East opponents that held a losing record.
- Byron Buxton ranks 5th amongst qualified players for Slugging Percentage (.572) this season.
Washington Nationals Player Prop Facts
- MacKenzie Gore has recorded six or more strikeouts in nine of his last 10 road appearances.
- Josh Bell has recorded at least one hit in each of his last 10 road appearances against opponents that held a losing record.
- Paul DeJong has hit a home run in three of his last four road appearances against AL Central opponents.
- Josh Bell has recorded a Double in three of his last four appearances after not playing the previous day.
- MacKenzie Gore ranks T6th in the league for total Strikeouts (140) this season.
Twins vs Nationals Prediction
The Twins are getting the benefit of the doubt because they’re the better team at home, but I’m not laying juice with Matthews, who has allowed 28 hits and 16 runs in 23 innings. Gore is an all-star who has a top-40 ERA and is top-10 in strikeouts. The Nationals obviously have issues of their own, but we’re getting the more favorable price with the better pitcher. You can do a lot worse than taking a shot with the Nats on Friday night.