Padres vs Dodgers Prediction 8/23/25 MLB Picks Today

The Los Angeles Dodgers and the San Diego Padres meet Saturday in MLB action from Petco Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Padres vs Dodgers Prediction.

Starting Pitching Matchup

The Los Angeles Dodgers will start Tyler Glasnow here and Glasnow is 1-1 with a 3.12 ERA and 72 strikeouts this season. In his career, Glasnow is 0-0 with a 3.00 ERA and 29 strikeouts against San Diego. Nestor Cortes will get the start for San Diego here and Cortes is 1-2 with a 5.87 ERA and 22 strikeouts this season. This will be Cortes’ second career start against the Dodgers.

Los Angeles Dodgers Recap

The Los Angeles Dodgers come into this game looking to rebound from their 2-1 loss at the hands of the Padres on Friday to sit at 73-56 this season. After this series, the Dodgers will head home for a series against the Cincinnati Reds.

Dodgers Alternate Wins & Losses In 6 Straight

Shohei Ohtani has 138 hits including 17 doubles, 44 home runs, 83 RBIs and 8 triples while Tommy Edman has 69 hits with 12 home runs and 44 RBIs. Michael Conforto has 63 hits with 18 doubles while Teoscar Hernandez has 101 hits with 21 home runs, 24 doubles and 76 RBIs as well this season. Ohtani has a team-high 17 stolen bases while Max Muncy has 10 doubles but also has 73 strikeouts so far this season. Mookie Betts has also chipped in 13 home runs and 57 RBIs as well on the year. Freddie Freeman has also logged 131 hits with a team-high 32 doubles, 16 home runs and 72 RBIs. Andy Pages also has 127 hits with 21 doubles, 21 home runs and 71 RBIs as well this season.

Why the Los Angeles Dodgers will win

• The Dodgers have won each of their last 14 games as favorites against NL West opponents following a road loss.
• The Padres have lost five of their last six games against the Dodgers following a win.
• The Dodgers have covered the run line in nine of their last 10 road games against NL West opponents following a loss.
• The Padres have failed to cover the run line in each of their last six Saturday night home games.

Los Angeles Dodgers Player Prop Facts

• Tyler Glasnow has recorded six or more strikeouts in 12 of his last 13 appearances in night games against NL teams that held a winning record.
• Miguel Rojas has recorded at least one hit in each of his last 12 appearances with the Dodgers as road favorites against NL West opponents.
• Tommy Edman has hit a home run in each of his last two appearances in night games against NL teams that held a winning record.
• Shohei Ohtani ranks 2nd amongst qualified players for Slugging Percentage (.621) this season.

San Diego Padres Recap

The San Diego Padres come into this game looking to add on to their win over the Dodgers on Friday to sit at 73-56 as well on the year. After this series, the Padres will head on the road for a series against the Seattle Mariners.

Padres Win Four Straight

Manny Machado has 145 hits including a team-high 32 doubles, 21 home runs, 77 RBIs and 12 stolen bases while Fernando Tatis Jr. has 128 hits with 17 home runs and 52 RBIs along with 25 stolen bases of his own this season. Luis Arraez has added 144 hits with 27 doubles, 4 triples, 6 home runs and 47 RBIs while Jackson Merrill’s added 91 hits with 9 home runs and 51 RBIs as well. Xander Bogaerts also has 28 doubles and 19 stolen bases as well this season. Gavin Sheets also has 18 doubles, 17 home runs and 58 RBIs as well this season.

Why the San Diego Padres will win

• The Padres have won five of their last six games as home underdogs.
• The Dodgers have lost six of their last eight games as road favorites.
• The Padres have covered the run line in each of their last 11 games as underdogs against National League opponents following a win.
• The Dodgers have failed to cover the run line in each of their last seven Saturday road games.

San Diego Padres Player Prop Facts

• Gavin Sheets has recorded at least one hit in each of his last 13 appearances against NL West opponents that held a winning record.
• Luis Campusano has hit a home run in three of his last six appearances at Petco Park against NL West opponents that held a winning record.
• Luis Arraez has recorded at least one Double in five of the Padres’ last six games against opponents that held a winning record.
• Manny Machado ranks 4th in the league in Hits (146) this season.

Total Runs Facts

• Fifteen of the Padres’ last 16 night games as underdogs have gone UNDER the total runs line.
• Five of the Dodgers’ last six night games against NL West opponents have gone UNDER the total runs line.

Padres vs Dodgers Prediction

I’m backing the Dodgers here. I get the case to be made for either side here, but I’m just not interested in backing Nestor Cortes here. The Dodgers’ offense has been inconsistent as of late, but they have picked up their play recently against left-handed pitching, and I think they get the job done in this one. Give me the Dodgers here.