Vanderbilt Commodores (2-0) vs. South Carolina Gamecocks (2-0)
September 13, 2025 7:45 pm EDT
The Line: South Carolina Gamecocks -4.5 / Vanderbilt Commodores 4.5; Over/Under: 48.5
(Get latest betting odds)
The Vanderbilt Commodores and South Carolina Gamecocks meet Saturday in college football action at Williams-Brice Stadium. Here’s a South Carolina vs Vanderbilt Prediction. This article will include a South Carolina vs Vanderbilt Pick.
Vanderbilt Commodores Betting Preview
The Vanderbilt Commodores beat Charleston Southern and Virginia Tech, and they play Georgia State next. The Vanderbilt Commodores have won 3 straight games. Diego Pavia is completing 74.4 percent of his passes for 468 yards, 5 touchdowns, and 1 interception. Tre Richardson and Eli Stowers have combined for 243 receiving yards and 2 touchdowns, while Junior Sherrill has 5 receptions.
The Vanderbilt Commodores ground game is averaging 231.5 yards per contest, and Sedrick Alexander leads the way with 156 yards and 2 touchdowns. Defensively, Vanderbilt is allowing 11.5 points and 191.5 yards per game. Martel Hight leads the Vanderbilt Commodores with 7 tackles, Hayden Bray has 1 sack and CJ Heard has 1 interception.
South Carolina Gamecocks Betting Preview
The South Carolina Gamecocks beat Virginia Tech and South Carolina State, and will play Missouri next. The South Carolina Gamecocks have won 8 straight regular season games. LaNorris Sellers is completing 60.5 percent of his passes for 337 yards, 2 touchdowns, and 0 interceptions. Nyck Harbor and Donovan Murph have combined for 159 receiving yards and 1 touchdown, while Vandrevius Jacobs has 4 receptions.
The South Carolina Gamecocks ground game is averaging 122 yards per contest, and Oscar Adaway III leads the way with 80 yards and 1 touchdown. Defensively, South Carolina is allowing 10.5 points and 303 yards per game. Fred Johnson leads the South Carolina Gamecocks with 13 tackles, Dylan Stewart has 2 sacks and Peyton Williams has 1 interception.
Vanderbilt Commodores @ South Carolina Gamecocks Betting Trends: Week 3
Why the South Carolina Gamecocks will win
- Vanderbilt has lost each of its last 10 September games against AP-ranked teams.
- South Carolina has won each of its last eight September games against non-AP-ranked teams.
- South Carolina has covered the spread in six of its last seven games against Vanderbilt.
- Vanderbilt has failed to cover the spread in 10 of its last 12 games against teams from South Carolina.
- South Carolina has won the first quarter in eight of its last nine home games against conference opponents.
- Vanderbilt has lost the first half in 38 of its last 45 games against conference opponents.
Why the Vanderbilt Commodores will win
- Vanderbilt has won three of its last four games as a road underdog.
- Vanderbilt has covered the spread in each of its last six games as a road underdog.
- The team ranked 11th in the AP Poll has failed to cover the spread in three of its last four games.
Total Points Facts
- Each of Vanderbilt’s last nine games in September have gone OVER the total points line.
- Each of South Carolina’s last four games have gone UNDER the total points line.
South Carolina Gamecocks Player Prop Facts
- Heading into Week 3, Vandrevius Jacobs ranks T1st amongst qualified players for catch rate (100.0%) this season.
Vanderbilt Commodores Player Prop Facts
- Heading into Week 3, Eli Stowers ranks T1st amongst qualified players for catch rate (100.0%) this season.
Matchup/League Facts
- South Carolina ranks T1st among FBS teams for Q3 opponent points per game this season (0.0).
- South Carolina ranks T1st among FBS teams for 4th down conversion percentage this season (100.0).
- Vanderbilt ranks T1st among FBS teams for Q3 opponent points per game this season (0.0).
- Vanderbilt ranks T1st among FBS teams for 4th down conversion percentage this season (100.0).
South Carolina vs Vanderbilt Prediction
Vanderbilt has covered 10 of its last 12 games as an underdog, and 6 of those covers were outright victories. You can talk yourself into the points in this SEC showdown. However, it feels like South Carolina is getting a soft line because of Vanderbilt has been a killer as an underdog lately.
South Carolina is the better, deeper team across the board with a Heisman caliber quarterback leading the charge, and the Gamecocks smoked the Commodores on the road back in November, 28-7. I’m not trying to step in front of this South Carolina squad, especially at home with the small chalk. I’ll take South Carolina by a touchdown on Saturday.
