College Football

Oklahoma vs Auburn Prediction Football Picks Today 9/20/25

Auburn Tigers (3-0) vs. Oklahoma Sooners (3-0)
September 20, 2025 3:30 pm EDT
The Line: Oklahoma Sooners -6 / Auburn Tigers 6; Over/Under: 48.5
(Get latest betting odds)

The Auburn Tigers and Oklahoma Sooners meet Saturday in college football action at Memorial Stadium. Here’s a Oklahoma vs Auburn Prediction. This article will include a Oklahoma vs Auburn Pick.

Auburn Tigers Betting Preview

The Auburn Tigers beat Ball State and South Alabama, and they play Texas A&M next. Auburn has won 5 of its last 6 games. Jackson Arnold is completing 69.6 percent of his passes for 501 yards, 4 touchdowns, and 0 interceptions. Eric Singleton Jr. and Cam Coleman have combined for 298 receiving yards and 3 touchdowns, while Horatio Fields has 10 receptions.


The Auburn Tigers ground game is averaging 242 yards per contest, and Jeremiah Cobb leads the way with 314 yards and 4 touchdowns. Defensively, Auburn is allowing 14 points and 287 yards per game. Keyron Crawford leads the Auburn Tigers with 16 tackles, Jared Smith has 2 sacks and Keldric Faulk has 2 pass deflections.

Oklahoma Sooners Betting Preview

The Oklahoma Sooners beat Michigan and Temple, and they play Kent State next. Oklahoma has split its last 10 games. John Mateer is completing 67.6 percent of his passes for 944 yards, 5 touchdowns, and 3 interceptions. Jaren Kanak and Deion Burks have combined for 470 receiving yards and 2 touchdowns, while Keontez Lewis has 15 receptions.

The Oklahoma Sooners ground game is averaging 156.3 yards per contest, and Tory Blaylock leads the way with 166 yards and 3 touchdowns. Defensively, Oklahoma is allowing 6.3 points and 181 yards per game. Sammy Omosigho leads the Oklahoma Sooners with 14 tackles, Taylor Wein has 1.5 sacks and Owen Heinecke has 2 pass deflections.

Auburn Tigers @ Oklahoma Sooners Betting Trends: Week 4

 

Why the Oklahoma Sooners will win

  • Auburn has lost each of its last eight road games against AP-ranked teams.
  • Oklahoma has won each of its last 13 games as a home favorite.
  • Oklahoma has covered the spread in eight of its last nine September games as a favorite.
  • Auburn has failed to cover the spread in each of its last four games in September.
  • Oklahoma has won the first half in 25 of its last 31 games against conference opponents at Oklahoma Memorial Stadium.

Why the Auburn Tigers will win

  • The team ranked 22nd in the AP Poll has won each of its last seven games.
  • Oklahoma has lost five of its last six games against conference opponents.
  • The team ranked 22nd in the AP Poll has covered the spread in each of its last six games.
  • The team ranked 11th in the AP Poll has failed to cover the spread in four of its last five games.

Total Points Facts

  • Eight of Oklahoma’s last nine games against AP-ranked teams at Oklahoma Memorial Stadium have gone UNDER the total points line.
  • Each of Auburn’s last four games as a road underdog have gone UNDER the total points line.

Oklahoma Sooners Player Prop Facts

  • Heading into Week 4, John Mateer ranks 7th amongst FBS players for passing yards (944) this season.

Auburn Tigers Player Prop Facts

  • Jackson Arnold has thrown zero interceptions in eight consecutive games – longest streak in the FBS, heading into Week 4.

Matchup/League Facts

  • Oklahoma ranks T1st among FBS teams for Q1 opponent points per game this season (0.0).
  • Oklahoma ranks T1st among FBS teams for Q4 opponent points per game this season (0.0).
  • Auburn ranks T1st among FBS teams for 4th down conversion percentage this season (100.0).
  • Auburn ranks T1st among FBS teams for red zone percentage this season (100.0).

Oklahoma vs Auburn Prediction

Oklahoma should be favored at home as it’s the better team and is more battle tested with a win over Michigan. However, Auburn is a good enough football team to take the points where you can get them. Auburn is explosive offensively, with a ground game averaging nearly 6 yards per touch, and the defense is getting after the quarterback consistently.

Auburn has a top-10 run defense and is 1 of 16 teams with double-digit sacks on the year. Auburn is capable of winning this game outright, and has covered 5 of its last 7 games as an underdog. Give me the free touchdown with Auburn on the road.

Randy Chambers's Free Pick: Auburn Tigers 6

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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