Seahawks vs Saints Prediction 9/21/25 NFL Picks Today

The New Orleans Saints and Seattle Seahawks meet Sunday in NFL action at Lumen Field. Here’s a Seahawks vs Saints Prediction. This article will include a Seahawks vs Saints Pick.

New Orleans Saints Betting Preview

The New Orleans Saints lost to the Cardinals and 49ers, and they play the Bills next. The New Orleans Saints have lost 6 straight games. Spencer Rattler is completing 65 percent of his passes for 421 yards, 3 touchdowns, and 0 interceptions. Juwan Johnson and Chris Olave have combined for 233 receiving yards and 1 touchdown, while Rashid Shaheed has 10 receptions.

The New Orleans Saints ground game is averaging 114 yards per contest, and Alvin Kamara leads the way with 144 yards and 1 touchdown. Defensively, New Orleans is allowing 23 points and 310 yards per game. Demario Davis leads the New Orleans Saints with 20 tackles, Carl Granderson has 3.5 sacks and Pete Werner has 2 pass deflections.

Seattle Seahawks Betting Preview

The Seattle Seahawks lost to the 49ers, beat the Steelers, and they play the Cardinals next. The Seahawks have won 7 of their last 10 games. Sam Darnold is completing 67.9 percent of his passes for 445 yards, 2 touchdowns, and 2 interceptions. Jaxon Smith-Njigba and Cooper Kupp have combined for 332 receiving yards on 26 catches, while Elijah Arroyo has 3 receptions.

The Seattle Seahawks ground game is averaging 100.5 yards per contest, and Kenneth Walker III leads the way with 125 yards and 1 touchdown. Defensively, Seattle is allowing 17 points and 325.5 yards per game. Ernest Jones IV leads the Seattle Seahawks with 18 tackles, Byron Murphy II has 1.5 sacks and Derion Kendrick has 1 interception.

New Orleans Saints @ Seattle Seahawks Betting Trends: Week 3

Why the Seattle Seahawks will win

• The Saints have lost each of their last six games.
• The favorites have won each of the Saints’ last eight games.
• The Saints have failed to cover the spread in each of their last six games as underdogs against NFC West opponents.
• The favorites have covered the spread in six of the Seahawks’ last seven games at Lumen Field.
• The Seahawks have scored the first touchdown in each of their last five games played as favorites on the West Coast.
• The Saints have lost the first half in seven of their last eight games against NFC West opponents.
• The Saints have lost the first quarter in five of their last six games.

Why the New Orleans Saints will win

• The underdogs have won each of the Saints’ last nine Week 3 games.
• The Seahawks have lost seven of their last eight home games.
• The underdogs have covered the spread in each of the Saints’ last 10 Week 3 games.
• The Seahawks have failed to cover the spread in each of their last six home games before a Division game.
• The Saints have scored the first touchdown in nine of their last 11 Week 3 games.
• The Saints have won the first half in seven of their last eight Week 3 games.
• The road team has won the first quarter in each of the Seahawks’ last seven games.

Total Points Facts

• Ten of the Seahawks’ last 11 home games against NFC South opponents have gone OVER the total points line.
• Each of the Saints’ last four Week 3 games have gone UNDER the total points line.
• Five of the last six Sunday games at Lumen Field have gone UNDER the total points line.

Seattle Seahawks Player Prop Facts

• Cooper Kupp has scored at least one touchdown in each of his last five Week 3 appearances.
• Kenneth Walker III has scored two or more touchdowns in three of the Seahawks’ last four September games against NFC opponents.
• Cooper Kupp has recorded 40+ receiving yards in each of his last 13 September appearances with his team as a favorite.
• Sam Darnold has recorded 231+ passing yards in each of his last 12 appearances with his team as a favorite.
• Kenneth Walker III has recorded 51+ rushing yards in each of his eight previous appearances with the Seahawks as favorites following a win.
• Cooper Kupp has recorded 40+ rushing and receiving yards in each of his last 13 September appearances with his team as a favorite.
• Sam Darnold has recorded 20+ completions in each of his last 10 appearances with his team as a favorite.
• Heading into Week 3, Boye Mafe ranks 1st in the NFL in quarterback hurries (4) this season.

New Orleans Saints Player Prop Facts

• Alvin Kamara has scored at least one touchdown in each of the Saints’ last four September games as road underdogs.
• Brandin Cooks has recorded 16+ receiving yards in each of his last 28 September appearances.
• Spencer Rattler has recorded 207+ passing yards in each of the Saints’ last four games.
• Alvin Kamara has recorded 58+ rushing yards in each of his last six Week 3 appearances.
• Brandin Cooks has recorded 19+ rushing and receiving yards in each of his 21 previous appearances with the Saints as underdogs.
• Spencer Rattler has recorded 25+ completions in each of the Saints’ last three games.
• Heading into Week 3, Carl Granderson ranks T1st in the NFL in sacks (3.5) this season.

Matchup/League Facts

• Seahawks – one different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 3.
• Seahawks – one different players have recorded 90+ rushing yards in a game this season – equal-most in the NFL, heading into Week 3.
• Saints – one different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 3.
• Saints – one different players have recorded 90+ rushing yards in a game this season – equal-most in the NFL, heading into Week 3.

Seahawks vs Saints Prediction

I’m not completely sold on the Seahawks, so laying full touchdown with them isn’t what I’m trying to do. However, this has more to do with the Saints than anything else. The Saints are the worst team in the league, they’re not winning dating back to last year, and they’re 4-9 ATS in their last 13 games as an underdog.

Outside of racking up 8 sacks in two games, there’s just not a lot to get excited about when it comes to the Saints, and they don’t cash tickets. Seattle is still a tough place to play and there’s upside with the Seahawks offensively. Thick number, but I’m not high on the Saints at all. Give me the Seahawks by double digits, but there are better options out there on Sunday’s NFL card.