Orioles vs Yankees Prediction 9/18/25 MLB Picks Today

In this article we will formulate an Orioles vs Yankees prediction for this MLB game on Thursday, September 18th at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 72-80 this year after they won all three against the White Sox by scores of 4-1, 8-7, and 3-1. In their game three win, Baltimore scored once in the first inning and twice in the fourth, which was enough to get the victory. The Orioles recorded seven hits in the game and they were led by Beavers, who went 1-3 with one home run and two RBIs in the win. Baltimore started Wells, who allowed four hits and one earned run over 6.0 innings for the win, while Akin picked up the save. 

Prior to that series, the Orioles lost all three against the Blue Jays, but won all three against the Pirates before that. Baltimore has won six of their last nine games and they are last in the AL East standings. The Baltimore pitching staff has a 4.59 ERA with a 1.37 WHIP and a .260 opponent batting average, while their offense has scored 650 runs with a .239 batting average and a .307 on base percentage this season. Jackson Holliday has led Baltimore with 17 home runs and 55 RBIs, while Gunnar Henderson has added 16 home runs and 64 RBIs this year. The projected starting pitcher for Baltimore is Cade Povich, who is 3-7 with a 5.05 ERA and a 1.45 WHIP over 101.2 innings pitched this year. 

New York Yankees Betting Preview

The New York Yankees are 85-67 this season after they won two out of three against Minnesota by scores of 0-7, 10-9, and 10-5. In their game three win, New York trailed 2-1 in the second inning, but scored the next six runs to create some separation for the win. The Yankees recorded 12 hits and they committed one error in the game, while they were led by Grisham, who went 2-5 with two home runs and four RBIs in the win. New York started Gil, who allowed nine hits and four earned runs over 4.2 innings, while Cruz got the win in relief. 

Prior to that series, the Yankees won two out of three against the Red Sox, but did lose two out of three against the Tigers before that. New York has won five of their last seven games and they are second in the AL East standings. The New York pitching staff has a 4.05 ERA with a 1.27 WHIP and a .233 opponent batting average, while the offense has scored 794 runs with a .250 batting average and a .330 on base percentage this season. Aaron Judge has led New York with 48 home runs and 103 RBIs, while Cody Bellinger has added 29 home runs and 97 RBIs this year. The projected starting pitcher for New York is Max Fried, who is 17-5 with a 3.03 ERA and a 1.13 WHIP over 181.1 innings pitched this season. 

Why the Orioles will beat the Yankees

• The Yankees have lost each of their last 10 night games against the Orioles following a win.
• The Orioles have won each of their last four games as underdogs following a road win.
• The Yankees have failed to cover the run line in 12 of their last 13 night games against the Orioles following a win.
• The underdogs have covered the run line in seven of the Orioles’ last eight games at Oriole Park at Camden Yards.
• The Yankees have trailed after 5 innings in three of their last four games at Oriole Park at Camden Yards.
• The Yankees have trailed after 3 innings in nine of their last 10 Thursday night games against opponents that held a losing record.

Why the Yankees will beat the Orioles

• The Orioles have lost each of their last seven games against AL East opponents.
• The Yankees have won 10 of their last 11 night games against teams that held a losing record.
• The Orioles have failed to cover the run line in nine of their last 10 games as home underdogs against AL East opponents following a road win.
• The Yankees have covered the run line each of their last five games against AL East opponents that held a losing record.
• The Yankees have led after 5 innings in eight of their last nine games as road favorites.
• The Yankees have won the first inning in six of their last seven games at Oriole Park at Camden Yards against opponents that held a losing record.
• The Yankees have led after 3 innings in each of their last four games as favorites against AL East opponents.

Total Runs Facts

• Each of the Orioles’ last 11 home games have gone UNDER the total runs line.
• Each of the Yankees’ last five games as favorites against AL East opponents have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the last five games between the Yankees and Orioles.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Yankees’ last five road games against AL East opponents.

Baltimore Orioles Player Prop Facts

• Dylan Carlson has recorded a Double in each of his last three home appearances against AL East opponents.
• Jordan Westburg has recorded at least one hit in each of his last seven home appearances after playing the previous day.
• Tyler O’Neill has hit a home run in three of his last four home appearances after playing the previous day.

New York Yankees Player Prop Facts

• Anthony Volpe has recorded at least one Double in each of the Yankees’ last three games as road favorites against the Orioles.
• Max Fried has recorded six or more strikeouts in each of his last 10 appearances in night games against teams that held a losing record.
• Max Fried has recorded a win in seven of his last eight appearances against opponents that held a losing record.
• Cody Bellinger has recorded at least one hit in each of his last 12 appearances with the Yankees as road favorites against AL East opponents.
• Giancarlo Stanton has hit at least one home run in each of the Yankees’ last three games against AL East opponents that held a losing record.

Orioles vs Yankees Prediction 

Baltimore comes into this matchup after sweeping the White Sox, but they are still last in the AL East standings. The Orioles are 36-38 on the road this year, while the Yankees are 41-36 at home. New York has scored 20 runs in their last two games and they are facing Povich, who has allowed 2, 4, 2, and 4 earned runs in his last four outings. Baltimore is going against Fried, who has allowed two earned runs or fewer in four of his last five starts. I think we are going to see plenty of scoring, as I don’t trust Povich and the Yankees bullpen has been brutal. Take the over here.