Carolina Panthers vs Dallas Cowboys Prediction 10/12/25 NFL Picks Today

The Dallas Cowboys and the Carolina Panthers meet in week 6 NFL action from Bank of America Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Dallas Cowboys vs. Carolina Panthers prediction.

Dallas Cowboys Recap

The Dallas Cowboys come into this game looking to build on a 37-22 win over the New York Jets last time out to sit at 2-2-1 this season. After this game, Dallas will head home for a game against the Washington Commanders.

Cowboys Looking To Build Momentum

Dak Prescott has thrown for 1,356 yards, 10 touchdowns and 3 interceptions on 71.3% passing while Javonte Williams leads the Cowboys in rushing with 447 rushing yards and 5 touchdowns so far this season. George Pickens leads the Cowboys in receiving with 357 yards and 5 touchdowns while Jake Ferguson has a team-high 42 catches for 272 yards and 3 TDs. Four more Cowboys have 100+ receiving yards as well on the year. On defense, Kenneth Murray Jr. has a team-high 35 total tackles including 17 solo tackles while James Houston has a team-high 3.5 sacks and the Cowboys’ defense as a whole has combined for 10 sacks and 3 interceptions so far this season. 

Why the Dallas Cowboys will win

• The Panthers have lost each of their last eight games at Bank of America Stadium following a win.
• The Cowboys have won each of their last nine October games as favorites.
• The Cowboys have covered the spread in each of their last nine October games as favorites.
• The Panthers have failed to cover the spread in eight of their last nine October home games against NFC opponents.

Dallas Cowboys Player Prop Facts

• George Pickens has scored at least one touchdown in seven of his last eight Sunday appearances.
• Jake Ferguson has recorded 69+ receiving yards in each of his last five Sunday appearances with the Cowboys as favorites.
• Javonte Williams has recorded 92+ rushing and receiving yards in each of the Cowboys’ last four games.
• Dak Prescott has recorded 10+ rushing yards in each of his last six October appearances with the Cowboys as road favorites.
• Dak Prescott has recorded 251+ passing yards in each of his last seven appearances with the Cowboys as favorites following a win.
• Dak Prescott has recorded 24+ completions in each of the Cowboys’ last 12 Sunday games as favorites.
• Heading into Week 6, Dak Prescott has recorded the most completions in a single game this season (38 vs Giants, Week 2).

Carolina Panthers Recap

The Carolina Panthers come into this game looking to add on to their 27-24 win over Miami in their last game to improve to 2-3 this season. After this game, the Carolina Panthers will head on the road for a game against the New York Jets.

Panthers Looking For Consistency

Bryce Young has thrown for 951 yards, 7 touchdowns and 4 interceptions on 60.9% passing while Rico Dowdle has a team-high 289 rushing yards and 2 TDs and Chuba Hubbard has 217 rushing yards as well this season. Tetairoa McMillan has a team-high 24 catches for 351 yards and Brycen Tremayne has 018 receiving yards as well on the year. On defense, Christian Rozeboom has a team-high 37 total tackles while Tre’von Moehrig has 36 total tackles with a team-high 24 solo tackles. As a unit, Carolina’s defense has combined for 5 sacks and 4 interceptions so far this season.

Why the Carolina Panthers will win

• The underdogs have won each of the Panthers’ last four games at Bank of America Stadium.
• The Cowboys have lost three of their last four Sunday games as favorites.
• The underdogs have covered the spread in each of the Panthers’ last seven games at Bank of America Stadium.
• The Cowboys have failed to cover the spread in each of their last four Sunday games as favorites.

Carolina Panthers Player Prop Facts

• Bryce Young has scored a touchdown in each of the Panthers’ last four home games against NFC opponents.
• Xavier Legette has recorded 23+ receiving yards in six of his last seven appearances at Bank of America Stadium.
• Rico Dowdle has recorded 84+ rushing and receiving yards in each of his last four appearances against NFC East opponents.
• Rico Dowdle has recorded 72+ rushing yards in each of his last four appearances against NFC East opponents.
• Andy Dalton has recorded 25+ completions in five of his six previous Week 6 home appearances.
• Heading into Week 6, Bryce Young has recorded the most pass attempts in a single game this season (55 vs Cardinals, Week 2).

Total Points Facts

• Each of the Cowboys’ last six games as favorites following a road win have gone OVER the total points line.
• Eight of the Panthers’ last nine games at Bank of America Stadium have gone OVER the total points line.

Dallas Cowboys vs. Carolina Panthers Prediction

I’m on the over in this one. Dallas continues to have one of the most electric offenses in the entire NFL, but a defense that can take their foot off of the gas at any time and also at times looks like they can’t even stop a nosebleed. I don’t know how many stops the Panthers get, but I’d be blind to not see that the Panthers have been far better at home so far this season. All in all, I have to roll with the over in this one as I’m expecting points once again.