Houston Cougars (4-1) vs. Oklahoma State Cowboys (1-4)
October 11, 2025 12:00 pm EDT
The Line: Oklahoma State Cowboys +14 / Houston Cougars -14; Over/Under: 47.5
(Get latest betting odds)
The Houston Cougars and the Oklahoma State Cowboys meet in week 7 college football action from Boone Pickens Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Houston Cougars vs. Oklahoma State Cowboys prediction.
Houston Cougars Recap
The Houston Cougars come into this game looking to bounce back fro a 35-11 loss to Texas Tech last time out to sit at 4-1 this season. After this game, Houston will head home for a game against Arizona.
Cougars Looking To Rebound From First Loss
Connor Weigman has thrown for 910 yards, 6 touchdowns and 2 interceptions on 59.3% passing while Dean Connors has rushed for 355 yards and 3 TDs on the ground this season. Weigman and Stacy Sneed each have 100+ rushing yards as well with Weigman adding 4 rushing TDs. Amare Thomas leads the Cougars with 284 receiving yards and 2 touchdowns while Stephon Johnson has 261 receiving yards and 2 TDs and Tanner Koziol has 244 receiving yards and a pair of scores as well this season. On defense, Jalen Garner and Carlos Allen Jr. each have a team-high 35 total tackles while Corey Platt Jr. has a team-high 2.5 sacks. As a unit, Houston’s defense has combined for 11 sacks and 5 interceptions so far this season.
Why the Houston Cougars will win
- Oklahoma State has lost each of its last 12 games against conference opponents.
- Houston has won each of its last 11 October games as a favorite.
- Oklahoma State has failed to cover the spread in nine of its last 10 games.
- Houston has covered the spread in each of its last four games in Oklahoma.
Oklahoma State Cowboys Recap
The Oklahoma State Cowboys come into this game looking to rebound from a 41-13 loss to Arizona in their last game to sit at 1-4 this season. After this game, Oklahoma State will take on Cincinnati at home.
Cowboys Drop 4th In A Row
Zane Flores has thrown for 696 yards and 3 INTs on 55% passing while Rodney Fields Jr. has rushed for a team-high 213 yards on 41 carries so far this season. Shamar Rigby has a team-high 11 catches for 154 yards while Terrill Davis has 149 receiving yards and Gavin Freeman has a team-high 16 catches for 144 yards and a touchdown. On defense, Bryan McCoy Jr. has team-high 37 total tackles while Wendell Gregory’s added a team-high 3 sacks for the Cowboys so far this season. As a unit, Oklahoma State has combined for 11 sacks and 3 interceptions so far this season.
Why the Oklahoma State Cowboys will win
- Oklahoma State has won each of its last five October games as a home underdog.
- Houston has lost five of its last six road games against conference opponents.
- Oklahoma State has covered the spread in each of its last five October games as a home underdog.
- Houston has failed to cover the spread in three of its last four road games against non-AP-ranked teams.
Total Points Facts
- Each of Oklahoma State’s last six games as a home underdog against teams from Texas have gone OVER the total points line.
- Each of Houston’s last five games as a road favorite have gone OVER the total points line.
Houston Cougars vs. Oklahoma State Cowboys Prediction
I’m on Houston here. I get the case to be made for a home underdog in spots, but this is just a bad Oklahoma State team that’s lost their three games against power conference opponents by 28, 18 and 66 this season. Houston got exposed last week by Texas Tech, who was the first team Houston played that had a pulse, but the Cougars had no problems for the most part outside of that and I don’t see Oklahoma State suddenly waking up in this game. Give me the Cougars laying the points.
