East Carolina vs Memphis Prediction Football Picks Today 11/15/25
Memphis Tigers (8-2) vs. East Carolina Pirates (6-3)
November 15, 2025 4:00 pm EDT
The Line: East Carolina Pirates -3 / Memphis Tigers +3; Over/Under: 57.5
(Get latest betting odds)
The Memphis Tigers and the East Carolina Pirates meet in week 12 college football action from Dowdy Ficklen Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Memphis Tigers vs. East Carolina Pirates prediction.
Memphis Tigers Recap
The Memphis Tigers come into this game looking to bounce back from their 38-32 loss at the hands of the Tulane Green Wave to sit at 8-2 this season. After this game, Memphis will have a bye before taking on Navy at home.
Tigers Have Two-Game Win Streak Snapped
Brendon Lewis leads Memphis in passing with 2,186 yards, 12 touchdowns and 5 interceptions while Sutton Smith leads Memphis on the ground with 535 rushing yards and 6 touchdowns so far this season. Lewis has also rushed for 521 yards with 8 TDs and Greg Desrosiers Jr. also has 485 rushing yards and 7 TDs. Cortez Braham Jr. leads Memphis’ receivers with 50 catches for 745 yards and 7 touchdowns while Jamari Hawkins has also chipped in 548 receiving yards as well this season. Sam Brumfield leads Memphis’ defense with 77 total tackles and 4.5 sacks while the Memphis defense as a whole has put up 16 sacks and 12 interceptions so far this season.
Why the Memphis Tigers will win
- Memphis has won each of its last five games as an underdog.
- Memphis has covered the spread in each of its last six games as an underdog.
- East Carolina has failed to cover the spread in four of its last five games against teams from Tennessee.
East Carolina Pirates Recap
The East Carolina Pirates come into this game looking to build on their 48-22 win over Charlotte last time out to sit at 6-3 this season. After this game, East Carolina will head on the road for a game against UTSA.
Pirates Win Three In A Row
Katin Houser leads ECU in passing with 2,469 passing yards, 14 touchdowns and 5 interceptions on 66.5% passing while London Montgomery leads the Pirates on the ground with 534 rushing yards and 5 TDs and Marlon Gunn Jr. has 320 rushing yards and 4 TDs as well. Anthony Smith leads ECU’s receiving group with 683 receiving yards, 44 catches and 4 TDs while Yannick Smith has 533 receiving yards and 5 TDs and Brock Spalding has 386 receiving yards and 2 TDs. Ja’Marley Riddle leads East Carolina’s defense with 49 total tackles including 26 solo tackles while East Carolina’s defense as a whole has combined for 24 sacks and 5 interceptions so far this season.Â
Why the East Carolina Pirates will win
- The favorite has won each of East Carolina’s last nine games.
- Memphis has failed to cover the spread in four of its last five games against teams from North Carolina.
Total Points Facts
- Eight of Memphis’ last nine games in November have gone OVER the total points line.
- Each of the last four games between Memphis and East Carolina have gone OVER the total points line.
Memphis Tigers vs. East Carolina Pirates Prediction
I’m on the over in this one. I get the case to be made for either side, but regardless of the QB situation for the Tigers whether Lewis is healthy or not, I think the Tigers can score some points here, I just think that ECU scores more. I do lean towards East Carolina for a side, but I think there’s going to be points whichever way it ends up going. Give me the over here.