Bills vs Bengals Prediction 12/7/25 NFL Picks Today
Cincinnati Bengals (4-8) vs. Buffalo Bills (8-4)
December 7, 2025 1:00 pm EDT
The Line: Buffalo Bills -5.5; Over/Under: 53.5
(Get latest betting odds)
The Cincinnati Bengals and the Buffalo Bills meet in week 14 NFL action from Highmark Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Bills vs Bengals Prediction.
Cincinnati Bengals Recap
The Cincinnati Bengals come into this game looking to add on to their 32-14 win over Baltimore last time out to sit at 4-8 this season. After this game, Cincinnati will head home for a rematch against the Ravens.
Bengals Snap Four-Game Losing Streak
Joe Flacco has thrown for 1,636 yards, 13 touchdowns and 4 interceptions on 61.6% passing while Joe Burrow has thrown for 450 yards and 4 touchdowns on 54.9% passing. Chase Brown has rushed for a team-high 704 yards and 2 touchdowns while Ja’Marr Chase leads Cincinnati’s receiving group with 86 catches for 971 yards and 5 touchdowns and Tee Higgins also has 575 receiving yards and 7 TDs as well. On defense, Jordan Battle has a team-high 92 total tackles while Demetrius Knight Jr. has 83 total tackles. Joseph Ossai has a team-high 5 sacks and Trey Hendrickson also has 4 sacks so far this season. As a unit, Cincinnati has combined for 17 sacks and 10 interceptions so far this season.Â
Why the Cincinnati Bengals will win
- The Bengals have won five of their last six December games as underdogs against AFC opponents.
- The Bills have lost each of their last three games as favorites when playing with a rest disadvantage.
- The Bengals have covered the spread in each of their last six Sunday games played on the East Coast.
- The Bills have failed to cover the spread in each of their last five games as favorites following a win.
Cincinnati Bengals Player Prop Facts
- Joe Burrow has recorded 261+ passing yards in each of his last six appearances in games with a total points line of at least 50.0.
- Ja’Marr Chase has scored at least one touchdown in four of the Bengals’ last five road games with a total points line of at least 50.0.
- Samaje Perine has recorded 21+ rushing yards in each of his last four appearances with the Bengals as underdogs following a win.
- Samaje Perine has recorded 29+ rushing and receiving yards in each of his last four December road appearances.
- Noah Fant has recorded 14+ receiving yards in each of his last 12 appearances following a win.
- Joe Flacco has recorded 21+ completions in seven of his last eight appearances against AFC opponents.
- Heading into Week 14, Ryan Rehkow ranks 1st amongst qualified players for gross average yards per punt (52.3) this season.
Buffalo Bills Recap
The Buffalo Bills come into this game looking to add on to their 26-7 win over Pittsburgh last time out to sit at 8-4 this season. After this game, the Bills will head on the road for a big division game against the New England Patriots.
Bills Alternate Wins & Losses In 4 Straight
Josh Allen has thrown for 2,832 yards, 19 touchdowns and 10 interceptions on 69.4% passing while also rushing for 409 yards and 11 scores. James Cook has a team-high 1,228 rushing yards and 8 touchdowns while Khalil Shakir has a team-high 55 catches for 569 yards and 3 TDs. Dalton Kincaid has 448 receiving yards, 4 touchdowns and 29 receptions and Keon Coleman has 34 catches for 339 yards and 4 TDs. On defense, Cole Bishop leads the Bills with 65 total tackles along with 3 interceptions while Joey Bosa has 5 sacks and the Bills’ defense as a whole has combined for 27 sacks and 8 interceptions so far this season.
Why the Buffalo Bills will win
- The Bills have won each of their last 18 games following a road win.
- The Bengals have lost each of their last 11 Sunday games as underdogs.
- The Bengals have failed to cover the spread in each of their last six games when playing with a rest advantage.
- The favorites have covered the spread in each of the Bengals’ last six Week 14 games.
Buffalo Bills Player Prop Facts
- Josh Allen has scored two touchdowns in three of the Bills’ last four home games with a total points line of at least 50.0.
- Josh Allen has recorded 21+ completions in nine of the Bills’ last 10 games with a total points line of at least 50.0.
- Josh Allen has recorded 253+ passing yards in each of the Bills’ last four games following a win.
- James Cook has recorded 125+ rushing and receiving yards in three of the Bills’ last four games against AFC opponents.
- Josh Allen has recorded 31+ rushing yards in seven of the Bills’ last eight Sunday games as favorites.
- James Cook has scored at least one touchdown in eight of the Bills’ last nine games as home favorites.
- Dawson Knox has recorded 28+ receiving yards in each of his six previous regular season appearances with the Bills as favorites against AFC North opponents.
- Heading into Week 14, James Cook is the only player to have recorded 1000+ rushing yards in each of the last three seasons. (including 2025).
Total Points Facts
- Each of the Bills’ last six home games without Dawson Knox have gone UNDER the total points line.
- Eight of the Bengals’ last nine games without Tanner Hudson have gone OVER the total points line.
Bills vs Bengals Prediction
I’m on the Bengals and the points in this one. I just think this is a spot where Cincinnati’s offense looked rejuvenated with Joe Burrow back under center, and at their peak, Cincinnati has one of the most explosive offenses in the entire NFL. Buffalo is one of the NFL’s best and is in a must-win situation with New England on a bye and a chance to make up some ground in the division race. However, this feels like a game where Cincinnati can go score for score with Buffalo. This feels like a 34-31 kind of game. Give me the points with Cincinnati.