Celtics vs Pacers Prediction 12/22/25 NBA Picks Today
Indiana Pacers (6-22) vs. Boston Celtics (17-11)
December 22, 2025 7:30 pm EDT
The Line: Boston Celtics -10.5; Over/Under: 224.5
(Get latest betting odds)
The Indiana Pacers and Boston Celtics meet Monday in NBA action at the TD Garden. Here’s a Celtics vs Pacers Prediction. This article will include a Celtics vs Pacers Pick.
Indiana Pacers Betting Preview
The Indiana Pacers lost to the Knicks and Pelicans, and they play the Bucks next. The Pacers have lost 22 of their last 28 games.
The Indiana Pacers are averaging 110.2 points on 43 percent shooting and allowing 118.3 points on 47.5 percent shooting. Pascal Siakam is averaging 23.8 points and 6.8 rebounds, while Bennedict Mathurin is averaging 20.1 points and 5.5 rebounds. Andrew Nembhard is the third double-digit scorer, and Aaron Nesmith is grabbing 4.5 rebounds. The Indiana Pacers are shooting 32.9 percent from beyond the arc and 77.8 percent from the free-throw line. The Indiana Pacers are allowing 33.4 percent shooting from deep and are grabbing 43.9 rebounds per game.
Boston Celtics Betting Preview
The Boston Celtics beat the Heat and Raptors, and they play the Pacers next. The Celtics have won 12 of their last 16 games.
The Boston Celtics are averaging 116.8 points on 47 percent shooting and allowing 110.8 points on 45.1 percent shooting. Jaylen Brown is averaging 29.1 points and 6.1 rebounds, while Derrick White is averaging 17.2 points and 4 rebounds. Payton Pritchard is the third double-digit scorer and Anfernee Simons is grabbing 2.2 rebounds. The Boston Celtics are shooting 36.5 percent from beyond the arc and 78.5 percent from the free throw line. The Boston Celtics are allowing 37.2 percent shooting from deep and are grabbing 43.6 rebounds per game.
Why the Boston Celtics will win
- The Pacers have lost each of their last 12 games against teams that held a winning record.
- The Celtics have won 10 of their last 11 home games against the Pacers following a win.
- The Pacers have failed to cover the spread in eight of their last nine games on the first leg of a back-to-back.
- The Celtics have covered the spread in seven of their last eight games following a win.
Why the Indiana Pacers will win
- The Celtics have lost each of their last four games as favorites against Central Division opponents.
- The underdogs have won three of the Celtics’ last four games.
- The Celtics have failed to cover the spread in each of their last eight games as favorites against Central Division opponents following a win.
- The Pacers have covered the spread in each of their last five games as underdogs against Eastern Conference opponents following a loss.
Total Points Facts
- Each of the Pacers’ last seven road games on the first leg of a back-to-back have gone UNDER the total points line.
- Each of the Celtics’ last six home games against the Pacers have gone OVER the total points line.
Celtics vs Pacers Injury Report
The Celtics will be without Jayson Tatum due to an Achilles injury. Jaylen Brown and Jordan Walsh are questionable.
The Pacers will be without Tyrese Haliburton, Obi Toppin, Aaron Nesmith, and Ben Sheppard. Johnny Furphy and T.J. McConnell are questionable.
Celtics vs Pacers Prediction
It would be nice to know if JB is going to go for the Celtics, but I’ll lay the points anyway. The Pacers just can’t get healthy, they don’t cover enough numbers to back consistently, and they’re 1-12 SU on the road. The Celtics have been one of the hotter teams in the league over the last few weeks, and they’re 8-2 ATS in their last 10 games. The underdog has covered 7 of the last 9 games between the Celtics and Pacers, so tread lightly. Still, the Pacers stink on the road and the Celtics are hot. I’ll lay the points.