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Xavier vs Creighton Prediction 1/21/26 College Basketball Picks Today

Xavier (11-7) vs. Creighton (11-8)
January 21, 2026 7:00 pm EDT
The Line: Creighton -8.5; Over/Under: 155.5
(Get latest betting odds)

In this article, we will formulate a Xavier vs Creighton Prediction for this College Basketball game on Wednesday, January 21st. Let’s take a look at the prediction for this College Basketball matchup.

Creighton Bluejays Preview

Creighton Bluejays have an 11-8 record this season and are in the 4th place of the Big East. They have a 5-3 conference record and are coming off a 93-88 away loss against Providence. Their previous three games were an 86-83 overtime home win against Georgetown, a 90-73 home loss against St. John’s and a 76-72 away win against Villanova.

Offensively, Creighton averages 78.2 points per game, while allowing 73.4 points per game defensively. The Bluejays shoot with 46% from the field and grab 36.4 rebounds per game, while dishing out 16 assists per game. They average 2.8 blocks per game and 5.9 steals per game defensively.

Josh Dix leads Creighton in scoring, with an average of 12.4 points per game, while shooting with 42.9% from the field and 86.5% from the free throw line. Jasen Green is the team’s leading rebounder with 5.2 per game. Nik Graves leads the team in assists with 3.4 per game.

Xavier Musketeers Preview

Xavier Musketeers have an 11-7 record this season and are tied in the 7th place of the Big East. They have a 3-4 conference record and are coming off an 89-75 home win against Butler. Their previous three games were a 97-84 home win against Providence, a 66-65 away loss against Marquette and an 86-77 away loss against DePaul.

Offensively, Xavier averages 77.4 points per game, while allowing 75.7 points per game defensively. The Musketeers shoot with 43% from the field and grab 35.9 rebounds per game, while dishing out 19.1 assists per game. They average 4.3 blocks per game and 7.2 steals per game defensively.

Tre Carroll leads Xavier in scoring, with an average of 16.7 points per game, while shooting with 48.4% from the field and 61.3% from the free throw line. Filip Borovicanin is the team’s leading rebounder with 7.9 per game and also leads the team in assists with 4.4 per game.

Xavier Musketeers @ Creighton Bluejays Betting Trends: January 21, 2026

 

Why the Creighton Bluejays will win

  • Creighton has won each of its last nine night games at CHI Health Center Omaha.
  • Xavier has lost each of its last four games at CHI Health Center Omaha following a home win.
  • Creighton has won the first half in each of its last 13 night games at CHI Health Center Omaha.

Why the Xavier Musketeers will win

  • Xavier has won six of its last eight night games.

Total Points Facts

  • Seven of Xavier’s last eight games against non-AP-ranked opponents at CHI Health Center Omaha have produced a total of 151 or fewer points.
  • Each of Creighton’s last four home games have produced a total of 161+ points.

Xavier vs Creighton Prediction

In this Xavier vs Creighton Prediction, Creighton is coming as -8 home favorites. Both teams have almost identical overall records and have exactly 11 wins each. Creighton has been very strong at home but has been up and down lately, with a 2-3 record in its last 5 games and 0-3 against the spread. Xaiver has been bad on the road but they are coming off back-to-back wins and are 3-0 against the spread, so I expect them to keep this one close. Take Xavier and get the +8 points in this one.

Nikos Lagouretos's Free Pick: Xavier +8.5

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