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Timberwolves vs 76ers Prediction 2/22/26 NBA Picks Today
Philadelphia 76ers (30-26) vs. Minnesota Timberwolves (35-22)
February 22, 2026 7:00 pm EDT
The Line: Minnesota Timberwolves -7.5; Over/Under: 236.5
(Get latest betting odds)
The Philadelphia 76ers invade the Target Center to battle the Minnesota Timberwolves on Sunday night. Here’s a Timberwolves vs. 76ers Prediction. This article will include a Timberwolves vs. 76ers pick.
Philadelphia 76ers Betting Preview
The Philadelphia 76ers have gone cold recently, as they’ve dropped five of their last six games overall, and they will be hoping to arrest a four-game slide after getting trounced by the Pelicans in a 126-111 road defeat last night. Tyrese Maxey led the team with 27 points and seven assists, Kelly Oubre Jr. added 25 points, and VJ Edgecombe chipped in with 14 points. As a team, the 76ers shot 38 percent from the field and 12 of 46 from the 3-point line as they stormed out of the gates with 65 points in the first half to lead by 11 points, but they were flat coming out of halftime and got blown out 69-46 in the second half to suffer a fourth straight defeat.
Minnesota Timberwolves Betting Preview
Meanwhile, the Minnesota Timberwolves have been in great shape as they’ve won eight of their last 11 games overall, and they will be aiming for a fourth straight victory after routing the depleted Mavericks in a 122-111 win on Friday. Anthony Edwards led the team with 40 points on 16 of 30 shooting, Rudy Gobert added 22 points with 17 rebounds and three blocks, while Naz Reid chipped in with 21 points, seven rebounds, and four assists off the bench. As a team, the Timberwolves set the tone with 40 points in the first quarter to set up an 18-point lead before Gobert committed a flagrant foul, which turned the momentum of the game. The Mavericks were allowed to climb all the way back into the contest, but fortunately, the Timberwolves turned to Edwards, who poured in 14 points in the fourth quarter to carry the team over the line.
Why the Minnesota Timberwolves will win
- The Timberwolves have won each of their last 13 home games against opponents who are on the second leg of a back-to-back.
- The 76ers have lost each of their last 10 games against Western Conference opponents after losing as favorites.
- The 76ers have failed to cover the spread in seven of their last eight games against Northwest Division opponents.
- The home team has covered the spread in each of the last four games between the 76ers and Timberwolves.
Why the Philadelphia 76ers will win
- The 76ers have won seven of their last eight night games following a road loss.
- The Timberwolves have lost four of their last five home games against 76ers teams that held a winning record.
- The 76ers have covered the spread in each of their last six road games on the second leg of a back-to-back.
- The Timberwolves have failed to cover the spread in four of their last five games against 76ers teams that held a winning record.
Total Points Facts
- Each of the 76ers’ last nine road games against Northwest Division opponents have gone OVER the total points line.
- Each of the Timberwolves’ last seven home games against opponents who are on the second leg of a back-to-back have gone UNDER the total points line.
Minnesota Timberwolves Player Facts
- Anthony Edwards ranks 3rd amongst qualified players for points per game (29.5) this season.
- Julius Randle is one of only three players in the league to have recorded 12+ assists without a turnover in a game this season.
Matchup/League Facts
- The Timberwolves have used only six different starting fives this season – fewest in the league.
- The Timberwolves rank 2nd in the league for opponent blocks per game this season (3.9).
- The 76ers rank 30th in the league for Q3 points per game this season (26.3).
- The 76ers rank 1st in the league for Q2 win percentage this season (69.6%).
Timberwolves vs 76ers Prediction
The 76ers are shorthanded once again with Joel Embiid still out, while the Timberwolves are coming in with a full squad once again. The 76ers have really struggled during this losing streak, and now they are playing on zero days’ rest against the Timberwolves, who are on a roll at the moment. This is the first meeting between these two squads, but based on recent form, I am comfortable taking the Timberwolves to continue their strong run with another win and cover at this reasonable line.



