Diamondbacks vs Pirates Prediction 5/7/26 MLB Picks Today
Pittsburgh Pirates (20-17) vs. Arizona Diamondbacks (17-18)
May 7, 2026 3:40 pm EDT
The Line: Arizona Diamondbacks -108 / Pittsburgh Pirates -112; Over/Under: 9
(Get latest betting odds)
The Pittsburgh Pirates and Arizona Diamondbacks meet Thursday in MLB action at Chase Field. Here’s a Diamondbacks vs. Pirates Prediction. This article will include a Diamondbacks vs. Pirates Pick.
Pittsburgh Pirates Betting Preview
The Pittsburgh Pirates are 20-17 on the year and play the Giants and Rockies next. The Pittsburgh Pirates are batting .247 on the season and have a .333 OBP, and a .387 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 3.75 ERA and a 1.22 WHIP. Nick Gonzales leads the Pittsburgh Pirates with 38 hits and 17 RBI, while Ryan O’Hearn and Oneil Cruz have combined for 74 hits and 52 RBI.
Mitch Keller gets the ball for the Pittsburgh Pirates, and he is 3-1 with a 2.85 ERA and 31 strikeouts this season. Keller is 1-0 with a 2.15 ERA and 25 strikeouts in his career against the Arizona Diamondbacks.
Arizona Diamondbacks Betting Preview
The Arizona Diamondbacks are 17-18 on the year and play the Mets and Rangers next. The Arizona Diamondbacks are batting. 244 on the season, have a .303 OBP, and have a .405 slugging percentage. The Arizona Diamondbacks’ pitching staff has a 4.80 ERA and a 1.37 WHIP. Ildemaro Vargas leads the Arizona Diamondbacks with 40 hits and 22 RBI while Nolan Arenado and Corbin Carroll have combined for 61 hits and 36 RBI.
Zac Gallen gets the ball for the Arizona Diamondbacks, and he is 1-2 with a 4.45 ERA and 20 strikeouts this season. Gallen is 3-4 with a 4.43 ERA and 33 strikeouts in his career against the Pittsburgh Pirates.
Why the Arizona Diamondbacks will win
- The Diamondbacks have won seven of their last eight games as home underdogs against NL Central opponents.
- The Pirates have lost four of their last five games as road favorites following a win.
- The Diamondbacks have covered the run line in each of their last eight games as home underdogs against NL Central opponents.
- The Pirates have failed to cover the run line in each of their last eight Thursday games as favorites against National League opponents.
- The Diamondbacks have won the first inning in six of their last seven home games against NL Central opponents.
- The Diamondbacks have led after 3 innings in seven of their last eight home games against NL Central opponents.
- The Diamondbacks have led after 5 innings in seven of their last eight home games against NL Central opponents.
Why the Pittsburgh Pirates will win
- The Diamondbacks have lost each of their last nine day games against NL Central opponents following a loss.
- The Pirates have won each of their last four games after playing the previous day.
- The Pirates have covered the run line in four of their last five games as road favorites.
- The Diamondbacks have failed to cover the run line in each of their last four games against NL Central opponents following a home loss.
- The Pirates have led after 5 innings in 11 of their last 12 games as favorites against NL West opponents.
- The Pirates have won the first inning in each of their last four games as road favorites against NL West opponents.
- The Diamondbacks have trailed after 3 innings in each of their last nine games as underdogs.
Total Runs Facts
- Five of the Diamondbacks’ last six games as underdogs against the Pirates have gone UNDER the total runs line.
- Eight of the Pirates’ last 10 day games after playing the previous day have gone OVER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Diamondbacks’ last seven games at Chase Field.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Pirates’ last five road games against NL West opponents.
Arizona Diamondbacks Player Prop Facts
- Lourdes Gurriel Jr. has recorded at least one hit in each of the Diamondbacks’ last eight home games against the Pirates.
- Zac Gallen has recorded five or more strikeouts in each of his last 10 appearances at Chase Field against NL opponents that held a winning record.
- Gabriel Moreno has hit a home run in three of his last nine appearances against NL Central opponents.
- Zac Gallen has recorded a win in four of his last five appearances at Chase Field.
Pittsburgh Pirates Player Prop Facts
- Mitch Keller has recorded five or more strikeouts in each of his last three appearances.
- Jared Triolo has hit a home run in each of his last two appearances with the Pirates as favorites against NL West opponents.
- Mitch Keller has recorded a win in four of his last five appearances against NL West opponents that held a losing record.
- Oneil Cruz has recorded at least one hit in 14 of his last 15 appearances in day games.
Matchup/League Facts
- The Diamondbacks rank 1st in the league for triples this season (11).
- The Diamondbacks rank 29th in the league for walks this season (95).
- The Pirates rank T1st in the league for home runs allowed this season (28).
- The Pirates rank T2nd in the league for strikeouts this season (342).
Diamondbacks vs Pirates Prediction
The Diamondbacks continue this rough week and you can argue this isn’t a great matchup either. Keller has been strong through 41 frames with a 2.85 ERA and 1.05 WHIP. Gallen hasn’t looked like himself with a 4.45 ERA and 1.52 WHIP through 32.1 innings. I get it. However, Gallen is one of the better arms in baseball when he’s right. He’s somebody who has received CY Young votes in three different seasons. It’s only a matter of time before he rights the ship. Also, the Diamondbacks are better than what they’ve shown up to this point. Give me the Diamondbacks at home in this pick ’em.