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Guardians vs Pirates Prediction 7/19/26 MLB Picks Today

Pittsburgh Pirates (51-48) vs. Cleveland Guardians (52-47)
July 19, 2026 1:40 pm EDT
The Line: Cleveland Guardians 105 / Pittsburgh Pirates -127; Over/Under: 7
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In this article we will formulate a Guardians vs Pirates prediction for this MLB game on Sunday, July 19th at Progressive Field in Cleveland, Ohio. Let’s take a look at the prediction for this MLB matchup. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 52-47 this year after they split the first two games in this series by scores of 1-7 and 5-3. In game two, Cleveland trailed 3-0 in the fourth inning, but they scored three in the eighth and two in the ninth for the win. The Guardians recorded 11 hits and they committed one error in the game, while they were led by Bazzana, who went 2-3 with one home run and two RBIs. Allen allowed six hits and two earned runs over 3.1 innings, while Smith picked up the win in relief. Prior to this series, Cleveland swept the Marlins in three games, but lost two out of three against the Twins before that. 

This season, Cleveland has a 3.73 ERA with a 1.26 WHIP and a .237 opponent batting average, while they have scored 391 runs with a .230 batting average and a .310 on base percentage. Chase DeLauter has led the Guardians with 11 home runs and 47 RBIs, while Angel Martinez has added 11 home runs and 33 RBIs. The projected starting pitcher for Cleveland is Tanner Bibee, who is 3-9 with a 3.90 ERA and a 1.15 WHIP over 113.0 innings pitched this year. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 51-48 this season after they lost game two by a score of 3-5 on Saturday night. Pittsburgh scored three runs in the first four innings, but they failed to score over the last five innings for the bad loss. The Pirates recorded six hits in the game and they were led by Lowe, who went 1-2 with one RBI. Curtis allowed two hits and zero earned runs over 5.0 innings, while Soto blew the save and Santana got the loss. Prior to this series, Pittsburgh swept the Brewers in three games, but lost two out of three against the Braves before that. 

This season, Pittsburgh has a 4.30 ERA with a 1.32 WHIP and a .239 opponent batting average, while they have scored 526 runs with a .263 batting average and a .341 on base percentage. Brandon Lowe has led the Pirates with 21 home runs and 65 RBIs, while Ryan O’Hearn has added 16 home runs and 64 RBIs. The projected starting pitcher for Pittsburgh is Paul Skenes, who is 8-8 with a 3.57 ERA and a 1.02 WHIP over 108.1 innings pitched this season. 

Why the Cleveland Guardians will win

  • The Guardians have won each of their last four games as underdogs against the Pirates.
  • The Pirates have lost each of their last three games as favorites against the Guardians following a loss.
  • The Guardians have covered the run line in each of their last seven games as home underdogs following a win.
  • The Pirates have failed to cover the run line in seven of their last eight day games against AL Central opponents following a loss.
  • The Pirates have trailed after 3 innings in three of their last four games as road favorites.
  • The Guardians have led after 5 innings in six of their last seven day games against the Pirates.

Why the Pittsburgh Pirates will win

  • The Pirates have won seven of their last eight games against AL Central opponents.
  • The Guardians have lost six of their last seven games against National League opponents following a home win.
  • The Guardians have failed to cover the run line in each of their last seven home games following a win.
  • The Pirates have covered the run line in each of their last five games as road favorites against AL Central opponents.
  • The Pirates have won the first inning in six of their last eight day games against American League opponents that held a winning record.
  • The Pirates have led after 3 innings in each of their last six games against AL Central opponents that held a winning record.
  • The Pirates have led after 5 innings in each of their last seven games against American League opponents that held a winning record.

Total Runs Facts

  • Each of the Pirates’ last six games as favorites against American League opponents have gone OVER the total runs line.
  • Seven of the Guardians’ last eight games as underdogs against National League opponents have gone UNDER the total runs line.
  • There has been no run scored during the first inning in each of the Pirates’ last seven road games against AL Central opponents.
  • There has been no run scored during the first inning in 10 of the last 11 day games between the Pirates and Guardians.

Cleveland Guardians Player Prop Facts

  • Kyle Manzardo has hit a home run in each of the Guardians’ last two games as underdogs against the Pirates.
  • Joey Cantillo has recorded seven or more strikeouts in four of his last five appearances.
  • Steven Kwan has recorded at least one hit in each of the Guardians’ last 11 games against opponents that held a winning record.
  • Joey Cantillo has recorded a win in four of his last five appearances in day games.

Pittsburgh Pirates Player Prop Facts

  • Esmerlyn Valdez has hit at least one home run in four of the Pirates’ last five day games.
  • Bryan Reynolds has recorded at least one hit in each of his last 15 appearances in day games against AL Central teams that held a winning record.

Guardians vs Pirates Prediction 

Pittsburgh saw their winning streak come to an end on Saturday night, as their bullpen fell apart, but they have scored 7+ runs in three of their last five games. The Pirates are 24-24 on the road this year, while the Guardians are 25-23 at home. Cleveland has won four of their last five games and they have allowed three runs or fewer in all four wins. The Guardians are starting Bibee, who has allowed two earned runs or fewer in three of his last four starts, while Skenes has allowed two earned runs or fewer in three of his last five outings. Take the Pirates here, as we can’t pass up Skenes at this price. 

David Racey's Free Pick: Pirates ML

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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