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Nationals vs Cubs Prediction 8/12/26 MLB Picks Today

Chicago Cubs (70-50) vs. Washington Nationals (59-62)
August 12, 2026 6:45 pm EDT
The Line: Washington Nationals 141 / Chicago Cubs -171; Over/Under: 9.5
(Get latest betting odds)

The Chicago Cubs and Washington Nationals meet Wednesday in MLB action at Nationals Park. Here’s a Nationals vs Cubs Prediction. This article will include a Nationals vs Cubs Pick.

Chicago Cubs Betting Preview

The Chicago Cubs are 70-50 on the year and play the White Sox and Cardinals next. The Chicago Cubs are batting .250 on the season, with a .339 OBP and a .418 slugging percentage. The Chicago Cubs’ pitching staff has a 4.07 ERA and a 1.25 WHIP. Pete Crow-Armstrong leads the Chicago Cubs with 129 hits and 72 RBI, while Alex Bregman and Nico Hoerner have combined for 240 hits and 110 RBI.

David Peterson gets the ball for the Chicago Cubs, and he is 6-7 with a 5.35 ERA and 88 strikeouts this season. Peterson is 8-2 with a 3.10 ERA and 60 strikeouts in his career against the Washington Nationals.

Washington Nationals Betting Preview

The Washington Nationals are 59-62 on the year and play the Mets and Rangers next. The Washington Nationals are batting .252 on the season and have a .328 OBP and a .440 slugging percentage. The Washington Nationals’ pitching staff has a 4.73 ERA and a 1.39 WHIP. CJ Abrams leads the Washington Nationals with 127 hits and 91 RBI, while James Wood and Daylen Lile have combined for 227 hits and 134 RBI.

Miles Mikolas gets the ball for the Washington Nationals, and he is 3-9 with a 5.89 ERA and 56 strikeouts this season. Mikolas is 6-9 with a 3.86 ERA and 100 strikeouts in his career against the Chicago Cubs.

Why the Washington Nationals will win

  • The Nationals have won each of their last four games as underdogs against the Cubs following a loss.
  • The Cubs have lost three of their last four games as favorites against the Nationals following a win.
  • The Nationals have covered the run line in each of their last six night games against NL Central opponents following a loss.
  • The Cubs have failed to cover the run line in eight of their last 10 night games at Nationals Park following a road win.
  • The Nationals have led after 3 innings in each of their last three games.
  • The Nationals have led after 5 innings in five of their last six home games.
  • The Cubs have lost the first inning in four of their last five games.

Why the Chicago Cubs will win

  • The Cubs have won each of their last 13 games against NL East opponents that held a losing record.
  • The Nationals have lost 12 of their last 13 night games against teams that held a winning record.
  • The Cubs have covered the run line in each of their last eight road games against National League opponents after playing the previous day.
  • The Nationals have failed to cover the run line in seven of their last eight games against teams that held a winning record.
  • The Nationals have trailed after 3 innings in six of their last eight games against opponents that held a winning record.
  • The Nationals have trailed after 5 innings in seven of their last eight games against opponents that held a winning record.

Total Runs Facts

  • Each of the Nationals’ last four games as underdogs have gone OVER the total runs line.
  • Five of the Cubs’ last six games as favorites have gone OVER the total runs line.
  • There has been at least one run scored in the first inning in each of the Cubs’ last six games.
  • There has been at least one run scored in the first inning in nine of the last 10 night games between the Cubs and Nationals.

Washington Nationals Player Prop Facts

  • CJ Abrams has hit at least one home run in each of the Nationals’ last three home games against opponents that held a winning record.
  • CJ Abrams has recorded at least one hit in each of the Nationals’ last eight home games against NL opponents.
  • Nasim Nunez ranks 1st in the league in Steals (40) this season.

Chicago Cubs Player Prop Facts

  • Pete Crow-Armstrong has hit at least one home run in three of the Cubs’ last four games as favorites against NL opponents.
  • David Peterson has recorded five or more strikeouts in four of his last five appearances against the Nationals.
  • Alex Bregman has recorded at least one hit in each of the Cubs’ last eight games against NL opponents.
  • David Peterson has recorded a win in four of his last five appearances against the Nationals.
  • Pete Crow-Armstrong ranks 5th in the league in Steals (30) this season.

Matchup/League Facts

  • The Nationals rank 1st in the league for runs scored this season (649).
  • The Nationals rank 1st in the league for home runs this season (174).
  • The Cubs rank 1st in the league for on-base percentage this season (.339).
  • The Cubs rank 1st in the league for walks this season (513).

Nationals vs Cubs Prediction

I’m looking at the over in this spot. Peterson has a 5.35 ERA and 1.50 WHIP on the season, while Mikolas has a 5.82 ERA and 1.38 WHIP. Mikolas has allowed 21 hits and 10 runs in his last 11 innings and has allowed 3 or more runs in 5 of his last 6 starts. At home, Mikolas has a 5.98 ERA and a .284 allowed batting average. Expect some fireworks. Give me the over.

Randy Chambers's Free Pick: Over

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Randy Chambers

Randy has covered sports betting since 2014 and writes about everything from NFL to WNBA. Follow Randy Chambers on Twitter.

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