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Cubs vs Diamondbacks Prediction 8/24/26 MLB Picks Today

Chicago Cubs (75-56) vs. Arizona Diamondbacks (69-62)
August 24, 2026 9:40 pm EDT
The Line: Arizona Diamondbacks 123 / Chicago Cubs -149; Over/Under: 9
(Get latest betting odds)

In this article, we will formulate a Cubs vs Diamondbacks Prediction for this MLB matchup on Monday, August 24th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Arizona Diamondbacks Preview

The Arizona Diamondbacks have a 69-62 record this season and sit in 3rd place in the NL West. They have a 38-28 home record and are coming off a 5-3 home win against the Reds. They will face the Giants and the Phillies next.


The Arizona Diamondbacks have a .245 batting average this season, .318 OBP, and .401 Slugging percentage. Arizona’s pitching staff has a 4.19 ERA and 1.29 WHIP. Gabriel Moreno is the Diamondbacks’ best hitter with a .306 batting average. Ketel Marte leads the team in RBI with 67. Nolan Arenado adds a team-high 21 home runs.

Merrill Kelly (R) is the projected starting pitcher for the Diamondbacks, holding an 8-11 record, 5.37 ERA, and 1.52 WHIP.

Chicago Cubs Preview

The Chicago Cubs have a 75-56 record this season and sit in 2nd place in the NL Central. They have a 37-29 road record and are coming off a 19-2 road win against the Mariners. They will face the Reds and the Brewers next.

The Chicago Cubs have a .250 batting average this season, .339 OBP, and .423 Slugging percentage. Chicago’s pitching staff has a 4.12 ERA and 1.26 WHIP. Pete Crow-Armstrong is the Cubs’ best hitter with a .281 batting average, while leading the team in RBI with 83, adding a team-high 33 home runs.

Kevin Gausman (R) is the projected starting pitcher for the Cubs, holding a 6-11 record, 4.58 ERA, and 1.30 WHIP.

The Chicago Cubs @ Arizona Diamondbacks Betting Trends: August 24, 2026

 

  • Probable Starting Pitcher: Merrill Kelly      Record this season: 8-11      ERA: 5.37
  • Home Record: 4-4
  • Last 5 against Cubs: 1-1

Why the Arizona Diamondbacks will win

  • The Diamondbacks have won each of their last five games as home underdogs against the Cubs.
  • The Cubs have lost six of their last eight games as road favorites against NL West opponents following a road win.
  • The underdogs have covered the run line in 13 of the Cubs’ last 14 games at Chase Field.
  • The Cubs have failed to cover the run line in eight of their last nine games as road favorites against NL West opponents following a win.
  • The Cubs have trailed after 3 innings in each of their last four road night games.
  • The Diamondbacks have led after 5 innings in five of their last six games as underdogs against NL Central opponents.
  • The Diamondbacks have won the first inning in three of their last four night games at Chase Field.

 

  • Probable Starting Pitcher: Kevin Gausman      Record this season: 6-11      ERA: 4.58
  • Road Record: 3-6
  • Last 5 against Diamondbacks: 4-1

Why the Chicago Cubs will win

  • The Cubs have won each of their last 10 games against NL West opponents that held a winning record.
  • The Diamondbacks have lost seven of their last eight night games following a home win.
  • The Cubs have covered the run line in each of their last eight night games against National League opponents.
  • The Diamondbacks have failed to cover the run line in seven of their last eight night games against the Cubs at Chase Field following a home win.
  • The Cubs have led after 3 innings in each of their last seven games against the Diamondbacks.
  • The Cubs have led after 5 innings in seven of their last eight games against the Diamondbacks.
  • The Cubs have won the first inning in each of their last three night games.

Total Runs Facts

  • Each of the Diamondbacks’ last four games as home underdogs have gone UNDER the total runs line.
  • Six of the Cubs’ last seven road games have gone OVER the total runs line.
  • There has been at least one run scored in the first inning in each of the Diamondbacks’ last six night games against National League opponents.
  • There has been at least one run scored in the first inning in seven of the Cubs’ last eight games.

Arizona Diamondbacks Player Prop Facts

  • Ildemaro Vargas has hit a home run in each of the Diamondbacks’ last two games as underdogs against NL opponents.
  • Merrill Kelly has recorded a win in four of his last five home appearances against NL Central opponents.
  • Merrill Kelly has recorded five or more strikeouts in each of his nine previous appearances with his team as a home underdog against NL Central opponents.
  • Gabriel Moreno has recorded at least one hit in each of the Diamondbacks’ last 11 night games.
  • Gabriel Moreno ranks 5th amongst qualified players for Batting Average (.306) this season.

Chicago Cubs Player Prop Facts

  • Pete Crow-Armstrong has hit at least one home run in seven of the Cubs’ last eight games as favorites against NL West opponents.
  • Kevin Gausman has recorded six or more strikeouts in 14 of his last 16 appearances with his team as a road favorite against NL opponents.
  • Kevin Gausman has recorded a win in each of his last four road appearances against the Diamondbacks.
  • Seiya Suzuki has recorded at least one hit in 17 of his last 18 appearances against NL West opponents.
  • Pete Crow-Armstrong ranks 2nd amongst qualified players for Slugging Percentage (.559) this season.

Matchup/League Facts

  • The Diamondbacks rank 1st in the league for triples this season (35).
  • The Diamondbacks rank 2nd in the league for strikeouts against this season (951).
  • The Cubs rank 1st in the league for runs scored this season (684).
  • The Cubs rank 1st in the league for on-base percentage this season (.339).

Cubs vs Diamondbacks Prediction

The Cubs are 5-1 in their last 6 meetings against the Diamondbacks but have lost two of their last three visits in Arizona.

In this Cubs vs Diamondbacks Prediction, the Cubs are coming as -140 road favorites. Both pitchers have been in bad form, as Kelly has given up 5+ runs in three of his last four starts and sits on a 6.24 home ERA, while Gausman has a 6.19 ERA as a Cub. Both offenses have been clicking, as they average 10.1 runs per game combined in their last 10 and 12.4 combined in their last 5. Take the over 9 in this one.

 

Nikos Lagouretos's Free Pick: Over 9

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