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Pirates vs Giants Prediction 9/1/26 MLB Picks Today

San Francisco Giants (57-81) vs. Pittsburgh Pirates (67-71)
September 1, 2026 6:40 pm EDT
The Line: Pittsburgh Pirates -158 / San Francisco Giants 147; Over/Under: 7.5
(Get latest betting odds)

In this article we will formulate a Pirates vs Giants prediction for this MLB game on Tuesday, September 1st at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup. 

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 67-71 this season after they won two out of three against the Cardinals by scores of 1-4, 6-2, and 5-4. In game three, Pittsburgh led 4-0 in the fifth inning, but they barely hung on for the win. The Pirates recorded eight hits in the game and they were led by Valdez, who went 1-4 with one home run and two RBIs. Ashcraft allowed six hits and two earned runs over 5.0 innings for the win, while Montgomery picked up the save. Prior to that series, Pittsburgh won two out of three against the Padres, but lost all three against the Dodgers before that. 

This season, Pittsburgh has a 4.19 ERA with a 1.31 WHIP and a .237 opponent batting average, while they have scored 669 runs with a .252 batting average and a .329 on base percentage. Brandon Lowe has led the Pirates with 28 home runs and 82 RBIs, while Ryan O’Hearn has added 17 home runs and 69 RBIs. The projected starting pitcher for Pittsburgh is Paul Skenes, who is 9-11 with a 3.79 ERA and a 1.12 WHIP over 145.0 innings pitched this season. 

San Francisco Giants Betting Preview

The San Francisco Giants are 57-81 this year after they won a makeup game with the Braves by a score of 7-3 on Monday. San Francisco trailed 3-2 in the fifth inning, but they scored the last five runs for the win. The Giants recorded 11 hits and they committed one error in the game, while they were led by Cox, who went 2-5 with one home run and two RBIs. Molina allowed six hits and three earned runs over 5.0 innings for the win, while Foley picked up a hold. Prior to that makeup game, San Francisco split four games with the Diamondbacks and won two out of three against the Reds. 

This season, San Francisco has a 4.34 ERA with a 1.35 WHIP and a .248 opponent batting average, while they have scored 567 runs with a .247 batting average and a .307 on base percentage. Rafael Devers has led the Giants with 30 home runs and 79 RBIs, while Willy Adames has added 21 home runs and 51 RBIs. The projected starting pitcher for San Francisco is Logan Webb, who is 8-8 with a 3.72 ERA and a 1.10 WHIP over 147.2 innings pitched this year. 

Why the Pittsburgh Pirates will win

  • The Giants have lost each of their last seven games following a road win.
  • The Pirates have won five of their last six home games following a road win.
  • The Pirates have covered the run line in each of their last six home games following a road win.
  • The Giants have failed to cover the run line in each of their last four night games against the Pirates following a win.
  • The Giants have trailed after 5 innings in each of their last four road games against NL opponents.
  • The Giants have lost the first inning in each of their last six Tuesday games as road underdogs.
  • The Giants have trailed after 3 innings in four of their last five road games against opponents that held a losing record.

Why the San Francisco Giants will win

  • The Giants have won each of their last five games as road underdogs against the Pirates following a win.
  • The Pirates have lost each of their last four games as favorites against NL West opponents following a road win.
  • The Pirates have failed to cover the run line in each of their last six home games against NL West opponents following a win.
  • The Giants have covered the run line in each of their last six games as road underdogs against the Pirates following a win.
  • The Giants have won the first inning in three of their last four games against NL opponents that held a losing record.
  • The Giants have led after 3 innings in five of their last six night games against NL opponents that held a losing record.
  • The Giants have led after 5 innings in eight of their last nine night games against NL Central opponents that held a losing record.

Total Runs Facts

  • Seven of the Giants’ last eight night games against NL Central opponents have gone UNDER the total runs line.
  • Each of the Pirates’ last five games against NL West opponents have gone UNDER the total runs line.
  • There has been at least one run scored in the first inning in each of the Giants’ last seven night games.
  • There has been no run scored during the first inning in each of the Pirates’ last four games as favorites against NL opponents.

Pittsburgh Pirates Player Prop Facts

  • Oneil Cruz has hit a home run in three of his last four appearances after not playing the previous day.
  • Paul Skenes has recorded a win in five of his last six home appearances against NL West opponents.
  • Paul Skenes has recorded seven or more strikeouts in each of his last six appearances against NL West opponents that held a losing record.
  • Bryan Reynolds has recorded at least one hit in each of the Pirates’ last 14 games as favorites against NL West opponents.
  • Nick Gonzales ranks 4th amongst qualified players for Batting Average (.307) this season.

San Francisco Giants Player Prop Facts

  • Rafael Devers has hit a home run in each of the Giants’ last four games against NL opponents that held a losing record.
  • Logan Webb has recorded a win in each of his last three road appearances against NL Central opponents.
  • Logan Webb has recorded five or more strikeouts in each of his last 14 appearances against NL Central opponents that held a losing record.
  • Rafael Devers has recorded at least one hit in each of the Giants’ last 13 games against NL opponents.
  • Rafael Devers ranks T10th in the league in Home Runs (30) this season.

Matchup/League Facts

  • The Pirates rank 30th in the league for strikeouts against this season (1317).
  • The Pirates rank T2nd in the league for hits this season (1197).
  • The Giants rank 30th in the league for walks this season (372).
  • The Giants rank 1st in the league for home runs allowed this season (129).

Pirates vs Giants Prediction 

Pittsburgh comes into this matchup after winning a series against the Cardinals and they scored 11 runs in their last two games. The Pirates are 34-32 at home this year, while the Giants are 24-45 on the road. San Francisco has also won two in a row and they have scored 6+ runs in three of their last four. The Giants are starting Webb, who has allowed two earned runs or fewer in four of his last five outings, while Skenes has allowed one earned run or fewer in two of his last three starts. Take the under here. 

David Racey's Free Pick: Under 7.5

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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