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Marlins vs Cubs Prediction 9/6/26 MLB Picks Today

Chicago Cubs (81-62) vs. Miami Marlins (71-72)
September 6, 2026 1:40 pm EDT
The Line: Miami Marlins 123 / Chicago Cubs -149; Over/Under: 8
(Get latest betting odds)

In this article we will formulate a Marlins vs Cubs prediction for this MLB game on Sunday, September 6th at loanDepot park in Miami, Florida. Let’s take a look at the prediction for this MLB matchup. 

Miami Marlins Betting Preview

The Miami Marlins are 71-72 this year after they lost the first two games by scores of 1-6 and 5-6. In game two, Miami cut the deficit to 6-5 in the seventh inning, but couldn’t find the tying run in the loss. The Marlins recorded six hits in the game and they were led by Conine, who went 1-2 with one home run and two RBIs. Gusto allowed 10 hits and five earned runs over 4.2 innings for the loss, while Vodnik allowed one earned run in relief. Prior to this series, Miami won two out of three against the Royals, but lost three out of four against the Nationals before that. 


This season, Miami has a 3.99 ERA with a 1.26 WHIP and a .233 opponent batting average, while they have scored 621 runs with a .247 batting average and a .325 on base percentage. Otto Lopez has led the Marlins with 10 home runs and 62 RBIs, while Owen Caissie has added 13 home runs and 53 RBIs. The projected starting pitcher for Miami is Tyler Phillips, who is 4-6 with a 3.43 ERA and a 1.33 WHIP over 110.1 innings pitched this year. 

Chicago Cubs Betting Preview

The Chicago Cubs are 81-62 this season after they won game two by a score of 6-5 on Saturday. Chicago led for just about the entire game, but barely hung on for the win. The Cubs recorded 13 hits in the game and they were led by Happ, who went 2-4 with two RBIs. Assad allowed three hits and three earned runs over 4.2 innings, while Rolison got the win in relief. Prior to this series, Chicago split four games with the Brewers and lost two out of three against the Reds. 

This season, Chicago has a 4.17 ERA with a 1.26 WHIP and a .244 opponent batting average, while they have scored 765 runs with a .252 batting average and a .340 on base percentage. Pete Crow-Armstrong has led the Cubs with 39 home runs and 94 RBIs, while Dansby Swanson has added 18 home runs and 66 RBIs. The projected starting pitcher for Chicago is Clay Holmes, who is 6-6 with a 2.09 ERA and a 1.07 WHIP over 81.2 innings pitched this season. 

Why the Miami Marlins will win

  • The underdogs have won seven of the Marlins’ last 10 games.
  • The Cubs have lost six of their last eight Sunday day games as road favorites against NL East opponents.
  • The Marlins have covered the run line in each of their last eight games as underdogs against NL Central opponents following a home loss.
  • The Cubs have failed to cover the run line in each of their last four day games following a win.
  • The Marlins have led after 3 innings in seven of their last nine day games against NL Central opponents that held a winning record.
  • The Marlins have led after 5 innings in each of their last six Sunday games against the Cubs.

Why the Chicago Cubs will win

  • The Marlins have lost each of their last eight games against NL opponents that held a winning record.
  • The Cubs have won 14 of their last 15 games against NL East opponents that held a losing record.
  • The Cubs have covered the run line in six of their last seven road games against teams that held a losing record.
  • The Marlins have failed to cover the run line in eight of their last 10 home games against NL opponents following a loss.
  • The Cubs have led after 3 innings in eight of their last nine games.
  • The Marlins have trailed after 5 innings in eight of their last nine games against NL opponents that held a winning record.
  • The Cubs have won the first inning in each of their last three games against opponents that held a losing record.

Total Runs Facts

  • Five of the Cubs’ last six games as favorites have gone OVER the total runs line.
  • Fifteen of the Marlins’ last 20 day games against NL Central opponents have gone UNDER the total runs line.
  • There has been no run scored during the first inning in each of the Marlins’ last 12 games against NL Central opponents.
  • There has been no run scored during the first inning in each of the Cubs’ last seven road games against NL opponents.

Miami Marlins Player Prop Facts

  • Griffin Conine has hit a home run in four of the Marlins’ last five day games against opponents that held a winning record.
  • Tyler Phillips has recorded four or more strikeouts in each of his last four home appearances.
  • Javier Sanoja has recorded at least one hit in each of the Marlins’ last nine games against NL opponents that held a winning record.
  • Otto Lopez ranks 2nd in the league in Hits (167) this season.

Chicago Cubs Player Prop Facts

  • Pete Crow-Armstrong has hit at least one home run in three of the Cubs’ last four games against opponents that held a losing record.
  • Pete Crow-Armstrong has recorded two or more hits in each of the Cubs’ last four games against opponents that held a losing record.
  • Clay Holmes has recorded five or more strikeouts in four of his last five appearances with his team as a road favorite.
  • Clay Holmes has recorded a win in each of his last three appearances with his team as a road favorite against NL East opponents.
  • Pete Crow-Armstrong ranks 2nd in the league in Home Runs (39) this season.

Matchup/League Facts

  • The Marlins rank T2nd in the league for triples this season (30).
  • The Marlins rank 2nd in the league for steals this season (146).
  • The Cubs rank 1st in the league for runs scored this season (765).
  • The Cubs rank 1st in the league for home runs this season (200).

Marlins vs Cubs Prediction 

Chicago comes into this matchup on a three game winning streak, but they continue to trail the Brewers by seven games. The Cubs are 40-31 on the road this year, while the Marlins are 42-29 at home. Miami has lost three in a row and they have allowed 6+ runs in four straight games. The Marlins are starting Phillips, who has allowed one earned run in his last 9.2 innings, while Holmes has allowed one earned run in his last 25.0 innings. Take the under here. 

David Racey's Free Pick: Under 8

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David Racey

David started writing about sports in 2015, but sports has been his passion for as long as he can remember. David spends most of his free time watching pretty much anything sports related from Baseball to Tennis and everything in between. David likes to analyze statistics and recent results to form an unbiased opinion on whatever game he is breaking down. Follow David on Twitter at @itsyerboi41

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